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dc.contributor.authorKeller Ab
dc.contributor.authorGraefen A
dc.contributor.authorBall M
dc.contributor.authorMatzas M
dc.contributor.authorBoisguerin V
dc.contributor.authorMaixner F
dc.contributor.authorLeidinger P
dc.contributor.authorBackes C
dc.contributor.authorKhairat R
dc.contributor.authorForster M
dc.contributor.authorStade B
dc.contributor.authorFranke A
dc.contributor.authorMayer J
dc.contributor.authorSpangler J
dc.contributor.authorMcLaughlin S
dc.contributor.authorShah M
dc.contributor.authorLee C
dc.contributor.authorHarkins T
dc.contributor.authorSartori A
dc.contributor.authorMoreno-Estrada A
dc.contributor.authorHenn B
dc.contributor.authorSikora M
dc.contributor.authorSemino O
dc.contributor.authorChiaroni J
dc.contributor.authorRootsi S
dc.contributor.authorMyres N
dc.contributor.authorCabrera V
dc.contributor.authorUnderhill P
dc.contributor.authorBustamante C
dc.contributor.authorVigl E
dc.contributor.authorSamadelli M
dc.contributor.authorCipollini G
dc.contributor.authorHaas J
dc.contributor.authorKatus H
dc.contributor.authorO'Connor Bq
dc.contributor.authorCarlson M
dc.contributor.authorMeder B
dc.contributor.authorBlin Ns
dc.contributor.authorMeese E
dc.contributor.authorPusch C
dc.contributor.authorZink A
dc.date.accessioned2018-09-27T13:19:03Z
dc.date.available2018-09-27T13:19:03Z
dc.date.issued2012
dc.identifier.issn2041-1723
dc.identifier.urihttp://dx.doi.org/10.1038/ncomms1701
dc.identifier.urihttp://hdl.handle.net/10863/6122
dc.description.abstractThe Tyrolean Iceman, a 5,300-year-old Copper age individual, was discovered in 1991 on the Tisenjoch Pass in the Italian part of the Ötztal Alps. Here we report the complete genome sequence of the Iceman and show 100% concordance between the previously reported mitochondrial genome sequence and the consensus sequence generated from our genomic data. We present indications for recent common ancestry between the Iceman and present-day inhabitants of the Tyrrhenian Sea, that the Iceman probably had brown eyes, belonged to blood group O and was lactose intolerant. His genetic predisposition shows an increased risk for coronary heart disease and may have contributed to the development of previously reported vascular calcifications. Sequences corresponding to ∼60% of the genome of Borrelia burgdorferi are indicative of the earliest human case of infection with the pathogen for Lyme borreliosis. © 2012 Macmillan Publishers Limited. All rights reserved.en_US
dc.language.isoenen_US
dc.rightsThis work is licensed under a Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License
dc.titleNew insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencingen_US
dc.typeArticleen_US
dc.date.updated2018-09-27T13:13:46Z
dc.language.isiEN-GB
dc.journal.titleNature Communications
dc.description.fulltextopenen_US


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