Now showing items 1-6 of 6

    • The 5300-year-old Helicobacter pylori genome of the Iceman 

      Maixner F; Krause-Kyora B; Turaev D; Herbig A; Hoopmann MR; Hallows JL; Kusebauch U; Vigl EE; Malfertheiner P; Megraud F; O'Sullivan N; Cipollini G; Coia V; Samadelli M; Engstrand L; Linz B; Moritz RL; Grimm R; Krause J; Nebel A; Moodley Y; Rattei T; Zink A (2016)
      The stomach bacterium Helicobacter pylori is one of the most prevalent human pathogens. It has dispersed globally with its human host resulting in a distinct phylogeographic pattern that can be used to reconstruct both ...
    • Demographic histories, isolation and social factors as determinants of the genetic structure of alpine linguistic groups 

      Coia V; Capocasa M; Anagnostou P; Pascali V; Scarnicci F; Boschi I; Battaggia C; Crivellaro F; Ferri G; Alù M; Brisighelli F; Busby G; Capelli C; Maixner F; Cipollini G; Viazzo P; Zink A; Bisol G (2013)
      Great European mountain ranges have acted as barriers to gene flow for resident populations since prehistory and have offered a place for the settlement of small, and sometimes culturally diverse, communities. Therefore, ...
    • The Iceman's Last Meal Consisted of Fat, Wild Meat, and Cereals 

      Maixner F; Turaev D; Cazenave-Gassiot A; Janko M; Krause-Kyora B; Hoopmann MR; Kusebauch U; Sartain M; Guerriero G; O'Sullivan N; Teasdale M; Cipollini G; Paladin A; Mattiangeli V; Samadelli M; Putzer A; Tecchiati U; Meissen J; Palazoglu M; Rausch P; Lösch S; Kim BJ; Baines JF; Gostner P; An HJ; Malfertheiner P; Egarter-Vigl E; Stark RW; Keller A; Bishop D; Wenk M; Engstrand L; Moritz RL; Bradley DG; Fiehn O; Nebel A; Oeggl K; Doble P; Franke A; Rattei T; Grimm R; Zink A (2018)
      The history of humankind is marked by the constant adoption of new dietary habits affecting human physiology, metabolism, and even the development of nutrition-related disorders. Despite clear archaeological evidence for ...
    • Metagenomic analysis reveals presence of Treponema denticola in a tissue biopsy of the Iceman 

      Maixner F; Thomma A; Cipollini G; Widder S; Rattei T; Zink A (2014)
      Ancient hominoid genome studies can be regarded by definition as metagenomic analyses since they represent a mixture of both hominoid and microbial sequences in an environment. Here, we report the molecular detection of ...
    • New insights into the Tyrolean Iceman's origin and phenotype as inferred by whole-genome sequencing 

      Keller Ab; Graefen A; Ball M; Matzas M; Boisguerin V; Maixner F; Leidinger P; Backes C; Khairat R; Forster M; Stade B; Franke A; Mayer J; Spangler J; McLaughlin S; Shah M; Lee C; Harkins T; Sartori A; Moreno-Estrada A; Henn B; Sikora M; Semino O; Chiaroni J; Rootsi S; Myres N; Cabrera V; Underhill P; Bustamante C; Vigl E; Samadelli M; Cipollini G; Haas J; Katus H; O'Connor Bq; Carlson M; Meder B; Blin Ns; Meese E; Pusch C; Zink A (2012)
      The Tyrolean Iceman, a 5,300-year-old Copper age individual, was discovered in 1991 on the Tisenjoch Pass in the Italian part of the Ötztal Alps. Here we report the complete genome sequence of the Iceman and show 100% ...
    • Whole mitochondrial DNA sequencing in Alpine populations and the genetic history of the Neolithic Tyrolean Iceman 

      Coia V; Cipollini G; Anagnostou P; Maixner F; Battaggia C; Brisighelli F; Gómez-Carballa A; Destro-Bisol G; Salas A; Zink A (2016)
      The Tyrolean Iceman is an extraordinarily well-preserved natural mummy that lived south of the Alpine ridge ∼5,200 years before present (ybp), during the Copper Age. Despite studies that have investigated his genetic ...