Now showing items 1-3 of 3

    • Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease 

      Tang W; Schwienbacher C; Lopez LM; Ben-Shlomo Y; Oudot-Mellakh T; Johnson AD; Samani NJ; Basu S; Gögele M; Davies G; Lowe GD; Tregouet DA; Tan A; Pankow JS; Tenesa A; Levy D; Volpato CB; Rumley A; Gow AJ; Minelli C; Yarnell JW; Porteous DJ; Starr JM; Gallacher J; Boerwinkle E; Visscher PM; Pramstaller PP; Cushman M; Emilsson V; Plump AS; Matijevic N; Morange PE; Deary IJ; Hicks AA; Folsom AR (2012)
      Activated partial thromboplastin time (aPTT) and prothrombin time (PT) are clinical tests commonly used to screen for coagulation-factor deficiencies. One genome-wide association study (GWAS) has been reported previously ...
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk 

      Dupuis J; Langenberg C; Prokopenko I; Saxena R; Soranzo N; Jackson AU; Wheeler E; Glazer NL; Bouatia-Naji N; Gloyn AL; Lindgren CM; Mägi R; Morris AP; Randall J; Johnson T; Elliott P; Rybin D; Thorleifsson G; Steinthorsdottir V; Henneman P; Grallert H; Dehghan A; Hottenga JJ; Franklin CS; Navarro P; Song K; Goel A; Perry JR; Egan JM; Lajunen T; Grarup N; Sparsø T; Doney A; Voight BF; Stringham HM; Li M; Kanoni S; Shrader P; Cavalcanti-Proença C; Kumari M; Qi L; Timpson NJ; Gieger C; Zabena C; Rocheleau G; Ingelsson E; An P; O'Connell J; Luan J; Elliott A; McCarroll SA; Payne F; Roccasecca RM; Pattou F; Sethupathy P; Ardlie K; Ariyurek Y; Balkau B; Barter P; Beilby JP; Ben-Shlomo Y; Benediktsson R; Bennett AJ; Bergmann S; Bochud M; Boerwinkle E; Bonnefond A; Bonnycastle LL; Borch-Johnsen K; Böttcher Y; Brunner E; Bumpstead SJ; Charpentier G; Chen YD; Chines P; Clarke R; Coin LJ; Cooper MN; Cornelis M; Crawford G; Crisponi L; Day IN; de Geus EJ; Delplanque J; Dina C; Erdos MR; Fedson AC; Fischer-Rosinsky A; Forouhi NG; Fox CS; Frants R; Franzosi MG; Galan P; Goodarzi MO; Graessler J; Groves CJ; Grundy S; Gwilliam R; Gyllensten U; Hadjadj S; Hallmans G; Hammond N; Han X; Hartikainen AL; Hassanali N; Hayward C; Heath SC; Hercberg S; Herder C; Hicks AA; Hillman DR; Hingorani AD; Hofman A; Hui J; Hung J; Isomaa B; Johnson PR; Jørgensen T; Jula A; Kaakinen M; Kaprio J; Kesaniemi YA; Kivimaki M; Knight B; Koskinen S; Kovacs P; Kyvik KO; Lathrop GM; Lawlor DA; Le Bacquer O; Lecoeur C; Li Y; Lyssenko V; Mahley R; Mangino M; Manning AK; Martínez-Larrad MT; McAteer JB; McCulloch LJ; McPherson R; Meisinger C; Melzer D; Meyre D; Mitchell BD; Morken MA; Mukherjee S; Naitza S; Narisu N; Neville MJ; Oostra BA; Orrù M; Pakyz R; Palmer CN; Paolisso G; Pattaro C; Pearson D; Peden JF; Pedersen NL; Perola M; Pfeiffer AF; Pichler I; Polasek O; Posthuma D; Potter SC; Pouta A; Province MA; Psaty BM; Rathmann W; Rayner NW; Rice K; Ripatti S; Rivadeneira F; Roden M; Rolandsson O; Sandbaek A; Sandhu M; Sanna S; Sayer AA; Scheet P; Scott LJ; Seedorf U; Sharp SJ; Shields B; Sigurethsson G; Sijbrands EJ; Silveira A; Simpson L; Singleton A; Smith NL; Sovio U; Swift A; Syddall H; Syvänen AC; Tanaka T; Thorand B; Tichet J; Tönjes A; Tuomi T; Uitterlinden AG; van Dijk KW; van Hoek M; Varma D; Visvikis-Siest S; Vitart V; Vogelzangs N; Waeber G; Wagner PJ; Walley A; Walters GB; Ward KL; Watkins H; Weedon MN; Wild SH; Willemsen G; Witteman JC; Yarnell JW; Zeggini E; Zelenika D; Zethelius B; Zhai G; Zhao JH; Zillikens MC; DIAGRAM Consortium; GIANT Consortium; Global BPgen Consortium; Borecki IB; Loos RJ; Meneton P; Magnusson PK; Nathan DM; Williams GH; Hattersley AT; Silander K; Salomaa V; Smith GD; Bornstein SR; Schwarz P; Spranger J; Karpe F; Shuldiner AR; Cooper C; Dedoussis GV; Serrano-Ríos M; Morris AD; Lind L; Palmer LJ; Hu FB; Franks PW; Ebrahim S; Marmot M; Kao WH; Pankow JS; Sampson MJ; Kuusisto J; Laakso M; Hansen T; Pedersen O; Pramstaller PP; Wichmann HE; Illig T; Rudan I; Wright AF; Stumvoll M; Campbell H; Wilson JF; Anders Hamsten on behalf of Procardis Consortium; MAGIC Investigators; Bergman RN; Buchanan TA; Collins FS; Mohlke KL; Tuomilehto J; Valle TT; Altshuler D; Rotter JI; Siscovick DS; Penninx BW; Boomsma DI; Deloukas P; Spector TD; Frayling TM; Ferrucci L; Kong A; Thorsteinsdottir U; Stefansson K; van Duijn CM; Aulchenko YS; Cao A; Scuteri A; Schlessinger D; Uda M; Ruokonen A; Jarvelin MR; Waterworth DM; Vollenweider P; Peltonen L; Mooser V; Abecasis GR; Wareham NJ; Sladek R; Froguel P; Watanabe RM; Meigs JB; Groop L; Boehnke M; McCarthy MI; Florez JC; Barroso I (2010)
      Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic traits, we performed meta-analyses of 21 genome-wide association studies informative for fasting glucose, fasting insulin and ...
    • Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits 

      Randall JC; Winkler TW; Kutalik Z; Berndt SI; Jackson AU; Monda KL; Kilpeläinen TO; Esko T; Mägi R; Li S; Workalemahu T; Feitosa MF; Croteau-Chonka DC; Day FR; Fall T; Ferreira T; Gustafsson S; Locke AE; Mathieson I; Scherag A; Vedantam S; Wood AR; Liang L; Steinthorsdottir V; Thorleifsson G; Dermitzakis ET; Dimas AS; Karpe F; Min JL; Nicholson G; Clegg DJ; Person T; Krohn JP; Bauer S; Buechler C; Eisinger K; DIAGRAM Consortium; Bonnefond A; Froguel P; MAGIC Investigators; Hottenga JJ; Prokopenko I; Waite LL; Harris TB; Smith AV; Shuldiner AR; McArdle WL; Caulfield MJ; Munroe PB; Grönberg H; Chen YD; Li G; Beckmann JS; Johnson T; Thorsteinsdottir U; Teder-Laving M; Khaw KT; Wareham NJ; Zhao JH; Amin N; Oostra BA; Kraja AT; Province MA; Cupples LA; Heard-Costa NL; Kaprio J; Ripatti S; Surakka I; Collins FS; Saramies J; Tuomilehto J; Jula A; Salomaa V; Erdmann J; Hengstenberg C; Loley C; Schunkert H; Lamina C; Wichmann HE; Albrecht E; Gieger C; Hicks AA; Johansson A; Pramstaller PP; Kathiresan S; Speliotes EK; Penninx B; Hartikainen AL; Jarvelin MR; Gyllensten U; Boomsma DI; Campbell H; Wilson JF; Chanock SJ; Farrall M; Goel A; Medina-Gomez C; Rivadeneira F; Estrada K; Uitterlinden AG; Hofman A; Zillikens MC; den Heijer M; Kiemeney LA; Maschio A; Hall P; Tyrer J; Teumer A; Völzke H; Kovacs P; Tönjes A; Mangino M; Spector TD; Hayward C; Rudan I; Hall AS; Samani NJ; Attwood AP; Sambrook JG; Hung J; Palmer LJ; Lokki ML; Sinisalo J; Boucher G; Huikuri H; Lorentzon M; Ohlsson C; Eklund N; Eriksson JG; Barlassina C; Rivolta C; Nolte IM; Snieder H; van der Klauw MM; van Vliet-Ostaptchouk JV; Gejman PV; Shi J; Jacobs KB; Wang Z; Bakker SJ; Mateo Leach I; Navis G; van der Harst P; Martin NG; Medland SE; Montgomery GW; Yang J; Chasman DI; Ridker PM; Rose LM; Lehtimäki T; Raitakari O; Absher D; Iribarren C; Basart H; Hovingh KG; Hyppönen E; Power C; Anderson D; Beilby JP; Hui J; Jolley J; Sager H; Bornstein SR; Schwarz PE; Kristiansson K; Perola M; Lindström J; Swift AJ; Uusitupa M; Atalay M; Lakka TA; Rauramaa R; Bolton JL; Fowkes G; Fraser RM; Price JF; Fischer K; Krjutå Kov K; Metspalu A; Mihailov E; Langenberg C; Luan J; Ong KK; Chines PS; Keinanen-Kiukaanniemi SM; Saaristo TE; Edkins S; Franks PW; Hallmans G; Shungin D; Morris AD; Palmer CN; Erbel R; Moebus S; Nöthen MM; Pechlivanis S; Hveem K; Narisu N; Hamsten A; Humphries SE; Strawbridge RJ; Tremoli E; Grallert H; Thorand B; Illig T; Koenig W; Müller-Nurasyid M; Peters A; Boehm BO; Kleber ME; März W; Winkelmann BR; Kuusisto J; Laakso M; Arveiler D; Cesana G; Kuulasmaa K; Virtamo J; Yarnell JW; Kuh D; Wong A; Lind L; de Faire U; Gigante B; Magnusson PK; Pedersen NL; Dedoussis G; Dimitriou M; Kolovou G; Kanoni S; Stirrups K; Bonnycastle LL; Njølstad I; Wilsgaard T; Ganna A; Rehnberg E; Hingorani A; Kivimaki M; Kumari M; Assimes TL; Barroso I; Boehnke M; Borecki IB; Deloukas P; Fox CS; Frayling T; Groop LC; Haritunians T; Hunter D; Ingelsson E; Kaplan R; Mohlke KL; O'Connell JR; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Abecasis GR; McCarthy MI; Hirschhorn JN; Qi L; Loos RJ; Lindgren CM; North KE; Heid IM (2013)
      Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass ...