Now showing items 1-2 of 2

    • Absence of previously reported variants in the SCNA (G88C and G209A), NR4A2 (T291D and T245G) and the DJ-1 (T497C) genes in familial Parkinson's disease from the GenePD study 

      Karamohamed S; Golbe LI; Mark MH; Lazzarini AM; Suchowersky O; Labelle N; Guttman M; Currie LJ; Wooten GF; Stacy M; Saint-Hilaire M; Feldman RG; Liu J; Shoemaker CM; Wilk JB; DeStefano AL; Latourelle JC; Xu G; Watts R; Growdon J; Lew M; Waters C; Vieregge P; Pramstaller PP; Klein C; Racette BA; Perlmutter JS; Parsian A; Singer C; Montgomery E; Baker K; Gusella JF; Herbert A; Myers RH (2005)
      Parkinson's disease (PD) is a neurodegenerative disorder in which relatives of the probands are affected approximately 4 times as frequently as relatives of control subjects. Several genes have been implicated as genetic ...
    • Influence of heterozygosity for parkin mutation on onset age in familial Parkinson disease: the GenePD study 

      Sun M; Latourelle JC; Wooten GF; Lew MF; Klein C; Shill HA; Golbe LI; Mark MH; Racette BA; Perlmutter JS; Parsian A; Guttman M; Nicholson G; Xu G; Wilk JB; Saint-Hilaire MH; DeStefano AL; Prakash R; Williamson S; Suchowersky O; Labelle N; Growdon JH; Singer C; Watts RL; Goldwurm S; Pezzoli G; Baker KB; Pramstaller PP; Burn DJ; Chinnery PF; Sherman S; Vieregge P; Litvan I; Gillis T; MacDonald ME; Myers RH; Gusella JF (2006)
      BACKGROUND: The PARK2 gene at 6q26 encodes parkin, whose inactivation is implicated in an early-onset autosomal recessive form of Parkinson disease (PD). OBJECTIVE: To evaluate the influence of heterozygosity for parkin ...