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    • Mutations in the mitochondrial thioredoxin reductase gene TXNRD2 cause dilated cardiomyopathy 

      Sibbing D; Pfeufer A; Perisic T; Mannes AM; Fritz-Wolf K; Unwin S; Sinner MF; Gieger C; Gloeckner CJ; Wichmann HE; Kremmer E; Schäfer Z; Walch A; Hinterseer M; Näbauer M; Kääb S; Kastrati A; Schömig A; Meitinger T; Bornkamm GW; Conrad M; von Beckerath N (2011)
      AIMS: Cardiac energy requirement is met to a large extent by oxidative phosphorylation in mitochondria that are highly abundant in cardiac myocytes. Human mitochondrial thioredoxin reductase (TXNRD2) is a selenocysteine ...