Now showing items 1-2 of 2

    • Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk 

      Warren HR; Evangelou E; Cabrera CP; Gao H; Ren M; Mifsud B; Ntalla I; Surendran P; Liu C; Cook JP; Kraja AT; Drenos F; Loh M; Verweij N; Marten J; Karaman I; Lepe MP; O'Reilly PF; Knight J; Snieder H; Kato N; He J; Tai ES; Said MA; Porteous D; Alver M; Poulter N; Farrall M; Gansevoort RT; Padmanabhan S; Mägi R; Stanton A; Connell J; Bakker SJ; Metspalu A; Shields DC; Thom S; Brown M; Sever P; Esko T; Hayward C; van der Harst P; Saleheen D; Chowdhury R; Chambers JC; Chasman DI; Chakravarti A; Newton-Cheh C; Lindgren CM; Levy D; Kooner JS; Keavney B; Tomaszewski M; Samani NJ; Howson JM; Tobin MD; Munroe PB; Ehret GB; Wain LV; International Consortium of Blood Pressure (ICBP) 1000G Analyses; BIOS Consortium; Lifelines Cohort Study; Understanding Society Scientific group; CHD Exome+ Consortium; ExomeBP Consortium; T2D-GENES Consortium; GoT2DGenes Consortium; CHARGE BP Exome Consortium; International Genomics of Blood Pressure (iGEN-BP) Consortium; UK Biobank CardioMetabolic Consortium BP working group (2017)
      Elevated blood pressure is the leading heritable risk factor for cardiovascular disease worldwide. We report genetic association of blood pressure (systolic, diastolic, pulse pressure) among UK Biobank participants of ...
    • Meta-analysis identifies common and rare variants influencing blood pressure and overlapping with metabolic trait loci 

      Liu C; Kraja AT; Smith JA; Brody JA; Franceschini N; Bis JC; Rice K; Morrison AC; Lu Y; Weiss S; Guo X; Palmas W; Martin LW; Chen YI; Surendran P; Drenos F; Cook JP; Auer PL; Chu AY; Giri A; Zhao W; Jakobsdottir J; Lin LA; Stafford JM; Amin N; Mei H; Yao J; Voorman A; CHD Exome+ Consortium; ExomeBP Consortium; GoT2DGenes Consortium; T2D-GENES Consortium; Larson MG; Grove ML; Smith AV; Hwang SJ; Chen H; Huan T; Kosova G; Stitziel NO; Kathiresan S; Samani N; Schunkert H; Deloukas P; Myocardial Infarction Genetics and CARDIoGRAM Exome Consortia; Li M; Fuchsberger C; Pattaro C; Gorski M; CKDGen Consortium; Kooperberg C; Papanicolaou GJ; Rossouw JE; Faul JD; Kardia SL; Bouchard C; Raffel LJ; Uitterlinden AG; Franco OH; Vasan RS; O'Donnell CJ; Taylor KD; Liu K; Bottinger EP; Gottesman O; Daw EW; Giulianini F; Ganesh S; Salfati E; Harris TB; Launer LJ; Dörr M; Felix SB; Rettig R; Völzke H; Kim E; Lee WJ; Lee IT; Sheu WH; Tsosie KS; Edwards DR; Liu Y; Correa A; Weir DR; Völker U; Ridker PM; Boerwinkle E; Gudnason V; Reiner AP; van Duijn CM; Borecki IB; Edwards TL; Chakravarti A; Rotter JI; Psaty BM; Loos RJ; Fornage M; Ehret GB; Newton-Cheh C; Levy D; Chasman DI (2016)
      Meta-analyses of association results for blood pressure using exome-centric single-variant and gene-based tests identified 31 new loci in a discovery stage among 146,562 individuals, with follow-up and meta-analysis in ...