Now showing items 1-2 of 2

    • New gene functions in megakaryopoiesis and platelet formation 

      Gieger C; Radhakrishnan A; Cvejic A; Tang W; Porcu E; Pistis G; Serbanovic-Canic J; Elling U; Goodall AH; Labrune Y; Lopez LM; Mägi R; Meacham S; Okada Y; Pirastu N; Sorice R; Teumer A; Voss K; Zhang W; Ramirez-Solis R; Bis JC; Ellinghaus D; Gögele M; Hottenga JJ; Langenberg C; Kovacs P; O'Reilly PF; Shin SY; Esko T; Hartiala J; Kanoni S; Murgia F; Parsa A; Stephens J; van der Harst P; Ellen van der Schoot C; Allayee H; Attwood A; Balkau B; Bastardot F; Basu S; Baumeister SE; Biino G; Bomba L; Bonnefond A; Cambien F; Chambers JC; Cucca F; D'Adamo P; Davies G; de Boer RA; de Geus EJ; Döring A; Elliott P; Erdmann J; Evans DM; Falchi M; Feng W; Folsom AR; Frazer IH; Gibson QD; Glazer NL; Hammond C; Hartikainen AL; Heckbert SR; Hengstenberg C; Hersch M; Illig T; Loos RJ; Jolley J; Khaw KT; Kühnel B; Kyrtsonis MC; Lagou V; Lloyd-Jones H; Lumley T; Mangino M; Maschio A; Mateo Leach I; McKnight B; Memari Y; Mitchell BD; Montgomery GW; Nakamura Y; Nauck M; Navis G; Nöthlings U; Nolte IM; Porteous DJ; Pouta A; Pramstaller PP; Pullat J; Ring SM; Rotter JI; Ruggiero D; Ruokonen A; Sala C; Samani NJ; Sambrook J; Schlessinger D; Schreiber S; Schunkert H; Scott J; Smith NL; Snieder H; Starr JM; Stumvoll M; Takahashi A; Tang WH; Taylor K; Tenesa A; Lay Thein S; Tönjes A; Uda M; Ulivi S; van Veldhuisen DJ; Visscher PM; Völker U; Wichmann HE; Wiggins KL; Willemsen G; Yang TP; Hua Zhao J; Zitting P; Bradley JR; Dedoussis GV; Gasparini P; Hazen SL; Metspalu A; Pirastu M; Shuldiner AR; Joost van Pelt L; Zwaginga JJ; Boomsma DI; Deary IJ; Franke A; Froguel P; Ganesh SK; Jarvelin MR; Martin NG; Meisinger C; Psaty BM; Spector TD; Wareham NJ; Akkerman JW; Ciullo M; Deloukas P; Greinacher A; Jupe S; Kamatani N; Khadake J; Kooner JS; Penninger J; Prokopenko I; Stemple D; Toniolo D; Wernisch L; Sanna S; Hicks AA; Rendon A; Ferreira MA; Ouwehand WH; Soranzo N (2011)
      Platelets are the second most abundant cell type in blood and are essential for maintaining haemostasis. Their count and volume are tightly controlled within narrow physiological ranges, but there is only limited understanding ...
    • Stratifying type 2 diabetes cases by BMI identifies genetic risk variants in LAMA1 and enrichment for risk variants in lean compared to obese cases 

      Perry JR; Voight BF; Yengo L; Amin N; Dupuis J; Ganser M; Grallert H; Navarro P; Li M; Qi L; Steinthorsdottir V; Scott RA; Almgren P; Arking DE; Aulchenko Y; Balkau B; Benediktsson R; Bergman RN; Boerwinkle E; Bonnycastle L; Burtt NP; Campbell H; Charpentier G; Collins FS; Gieger C; Green T; Hadjadj S; Hattersley AT; Herder C; Hofman A; Johnson AD; Kottgen A; Kraft P; Labrune Y; Langenberg C; Manning AK; Mohlke KL; Morris AP; Oostra B; Pankow J; Petersen AK; Pramstaller PP; Prokopenko I; Rathmann W; Rayner W; Roden M; Rudan I; Rybin D; Scott LJ; Sigurdsson G; Sladek R; Thorleifsson G; Thorsteinsdottir U; Tuomilehto J; Uitterlinden AG; Vivequin S; Weedon MN; Wright AF; MAGIC Consortium; DIAGRAM Consortium; GIANT Consortium; Hu FB; Illig T; Kao L; Meigs JB; Wilson JF; Stefansson K; van Duijn C; Altschuler D; Morris AD; Boehnke M; McCarthy MI; Froguel P; Palmer CN; Wareham NJ; Groop L; Frayling TM; Cauchi S (2012)
      Common diseases such as type 2 diabetes are phenotypically heterogeneous. Obesity is a major risk factor for type 2 diabetes, but patients vary appreciably in body mass index. We hypothesized that the genetic predisposition ...