Now showing items 1-7 of 7

    • Genetic studies of body mass index yield new insights for obesity biology 

      Locke AE; Kahali B; Berndt SI; Justice AE; Pers TH; Day FR; Powell C; Vedantam S; Buchkovich ML; Yang J; Croteau-Chonka DC; Esko T; Fall T; Ferreira T; Gustafsson S; Kutalik Z; Luan J; Mägi R; Randall JC; Winkler TW; Wood AR; Workalemahu T; Faul JD; Smith JA; Hua Zhao J; Zhao W; Chen J; Fehrmann R; Hedman ÅK; Karjalainen J; Schmidt EM; Absher D; Amin N; Anderson D; Beekman M; Bolton JL; Bragg-Gresham JL; Buyske S; Demirkan A; Deng G; Ehret GB; Feenstra B; Feitosa MF; Fischer K; Goel A; Gong J; Jackson AU; Kanoni S; Kleber ME; Kristiansson K; Lim U; Lotay V; Mangino M; Mateo Leach I; Medina-Gomez C; Medland SE; Nalls MA; Palmer CD; Pasko D; Pechlivanis S; Peters MJ; Prokopenko I; Shungin D; Stančáková A; Strawbridge RJ; Ju Sung Y; Tanaka T; Teumer A; Trompet S; van der Laan SW; van Setten J; van Vliet-Ostaptchouk JV; Wang Z; Yengo L; Zhang W; Isaacs A; Albrecht E; Ärnlöv J; Arscott GM; Attwood AP; Bandinelli S; Barrett A; Bas IN; Bellis C; Bennett AJ; Berne C; Blagieva R; Blüher M; Böhringer S; Bonnycastle LL; Böttcher Y; Boyd HA; Bruinenberg M; Caspersen IH; Ida Chen YD; Clarke R; Daw EW; de Craen AJ; Delgado G; Dimitriou M; Doney AS; Eklund N; Estrada K; Eury E; Folkersen L; Fraser RM; Garcia ME; Geller F; Giedraitis V; Gigante B; Go AS; Golay A; Goodall AH; Gordon SD; Gorski M; Grabe HJ; Grallert H; Grammer TB; Gräßler J; Grönberg H; Groves CJ; Gusto G; Haessler J; Hall P; Haller T; Hallmans G; Hartman CA; Hassinen M; Hayward C; Heard-Costa NL; Helmer Q; Hengstenberg C; Holmen O; Hottenga JJ; James AL; Jeff JM; Johansson Å; Jolley J; Juliusdottir T; Kinnunen L; Koenig W; Koskenvuo M; Kratzer W; Laitinen J; Lamina C; Leander K; Lee NR; Lichtner P; Lind L; Lindström J; Sin Lo K; Lobbens S; Lorbeer R; Lu Y; Mach F; Magnusson PK; Mahajan A; McArdle WL; McLachlan S; Menni C; Merger S; Mihailov E; Milani L; Moayyeri A; Monda KL; Morken MA; Mulas A; Müller G; Müller-Nurasyid M; Musk AW; Nagaraja R; Nöthen MM; Nolte IM; Pilz S; Rayner NW; Renstrom F; Rettig R; Ried JS; Ripke S; Robertson NR; Rose LM; Sanna S; Scharnagl H; Scholtens S; Schumacher FR; Scott WR; Seufferlein T; Shi J; Vernon Smith A; Smolonska J; Stanton AV; Steinthorsdottir V; Stirrups K; Stringham HM; Sundström J; Swertz MA; Swift AJ; Syvänen AC; Tan ST; Tayo BO; Thorand B; Thorleifsson G; Tyrer JP; Uh HW; Vandenput L; Verhulst FC; Vermeulen SH; Verweij N; Vonk JM; Waite LL; Warren HR; Waterworth D; Weedon MN; Wilkens LR; Willenborg C; Wilsgaard T; Wojczynski MK; Wong A; Wright AF; Zhang Q; LifeLines Cohort Study; Brennan EP; Choi M; Dastani Z; Drong AW; Eriksson P; Franco-Cereceda A; Gådin JR; Gharavi AG; Goddard ME; Handsaker RE; Huang J; Karpe F; Kathiresan S; Keildson S; Kiryluk K; Kubo M; Lee JY; Liang L; Lifton RP; Ma B; McCarroll SA; McKnight AJ; Min JL; Moffatt MF; Montgomery GW; Murabito JM; Nicholson G; Nyholt DR; Okada Y; Perry JR; Dorajoo R; Reinmaa E; Salem RM; Sandholm N; Scott RA; Stolk L; Takahashi A; Van't Hooft FM; Vinkhuyzen AA; Westra HJ; Zheng W; Zondervan KT; ADIPOGen Consortium; AGEN-BMI Working Group; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GLGC; ICBP; MAGIC Investigators; MuTHER Consortium; MIGen Consortium; PAGE Consortium; ReproGen Consortium; GENIE Consortium; International Endogene Consortium; Heath AC; Arveiler D; Bakker SJ; Beilby J; Bergman RN; Blangero J; Bovet P; Campbell H; Caulfield MJ; Cesana G; Chakravarti A; Chasman DI; Chines PS; Collins FS; Crawford DC; Cupples LA; Cusi D; Danesh J; de Faire U; den Ruijter HM; Dominiczak AF; Erbel R; Erdmann J; Eriksson JG; Farrall M; Felix SB; Ferrannini E; Ferrières J; Ford I; Forouhi NG; Forrester T; Franco OH; Gansevoort RT; Gejman PV; Gieger C; Gottesman O; Gudnason V; Gyllensten U; Hall AS; Harris TB; Hattersley AT; Hicks AA; Hindorff LA; Hingorani AD; Hofman A; Homuth G; Hovingh GK; Humphries SE; Hunt SC; Hyppönen E; Illig T; Jacobs KB; Jarvelin MR; Jöckel KH; Johansen B; Jousilahti P; Jukema JW; Jula AM; Kaprio J; Kastelein JJ; Keinanen-Kiukaanniemi SM; Kiemeney LA; Knekt P; Kooner JS; Kooperberg C; Kovacs P; Kraja AT; Kumari M; Kuusisto J; Lakka TA; Langenberg C; Le Marchand L; Lehtimäki T; Lyssenko V; Männistö S; Marette A; Matise TC; McKenzie CA; McKnight B; Moll FL; Morris AD; Morris AP; Murray JC; Nelis M; Ohlsson C; Oldehinkel AJ; Ong KK; Madden PA; Pasterkamp G; Peden JF; Peters A; Postma DS; Pramstaller PP; Price JF; Qi L; Raitakari OT; Rankinen T; Rao DC; Rice TK; Ridker PM; Rioux JD; Ritchie MD; Rudan I; Salomaa V; Samani NJ; Saramies J; Sarzynski MA; Schunkert H; Schwarz PE; Sever P; Shuldiner AR; Sinisalo J; Stolk RP; Strauch K; Tönjes A; Trégouët DA; Tremblay A; Tremoli E; Virtamo J; Vohl MC; Völker U; Waeber G; Willemsen G; Witteman JC; Zillikens MC; Adair LS; Amouyel P; Asselbergs FW; Assimes TL; Bochud M; Boehm BO; Boerwinkle E; Bornstein SR; Bottinger EP; Bouchard C; Cauchi S; Chambers JC; Chanock SJ; Cooper RS; de Bakker PI; Dedoussis G; Ferrucci L; Franks PW; Froguel P; Groop LC; Haiman CA; Hamsten A; Hui J; Hunter DJ; Hveem K; Kaplan RC; Kivimaki M; Kuh D; Laakso M; Liu Y; Martin NG; März W; Melbye M; Metspalu A; Moebus S; Munroe PB; Njølstad I; Oostra BA; Palmer CN; Pedersen NL; Perola M; Pérusse L; Peters U; Power C; Quertermous T; Rauramaa R; Rivadeneira F; Saaristo TE; Saleheen D; Sattar N; Schadt EE; Schlessinger D; Slagboom PE; Snieder H; Spector TD; Thorsteinsdottir U; Stumvoll M; Tuomilehto J; Uitterlinden AG; Uusitupa M; van der Harst P; Walker M; Wallaschofski H; Wareham NJ; Watkins H; Weir DR; Wichmann HE; Wilson JF; Zanen P; Borecki IB; Deloukas P; Fox CS; Heid IM; O'Connell JR; Strachan DP; Stefansson K; van Duijn CM; Abecasis GR; Franke L; Frayling TM; McCarthy MI; Visscher PM; Scherag A; Willer CJ; Boehnke M; Mohlke KL; Lindgren CM; Beckmann JS; Barroso I; North KE; Ingelsson E; Hirschhorn JN; Loos RJ; Speliotes EK (2015)
      Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body mass index (BMI), a measure ...
    • Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture 

      Berndt SI; Gustafsson S; Mägi R; Ganna A; Wheeler E; Feitosa MF; Justice AE; Monda KL; Croteau-Chonka DC; Day FR; Esko T; Fall T; Ferreira T; Gentilini D; Jackson AU; Luan J; Randall JC; Vedantam S; Willer CJ; Winkler TW; Wood AR; Workalemahu T; Hu YJ; Lee SH; Liang L; Lin DY; Min JL; Neale BM; Thorleifsson G; Yang J; Albrecht E; Amin N; Bragg-Gresham JL; Cadby G; den Heijer M; Eklund N; Fischer K; Goel A; Hottenga JJ; Huffman JE; Jarick I; Johansson Å; Johnson T; Kanoni S; Kleber ME; König IR; Kristiansson K; Kutalik Z; Lamina C; Lecoeur C; Li G; Mangino M; McArdle WL; Medina-Gomez C; Müller-Nurasyid M; Ngwa JS; Nolte IM; Paternoster L; Pechlivanis S; Perola M; Peters MJ; Preuss M; Rose LM; Shi J; Shungin D; Smith AV; Strawbridge RJ; Surakka I; Teumer A; Trip MD; Tyrer J; van Vliet-Ostaptchouk JV; Vandenput L; Waite LL; Zhao JH; Absher D; Asselbergs FW; Atalay M; Attwood AP; Balmforth AJ; Basart H; Beilby J; Bonnycastle LL; Brambilla P; Bruinenberg M; Campbell H; Chasman DI; Chines PS; Collins FS; Connell JM; Cookson WO; de Faire U; de Vegt F; Dei M; Dimitriou M; Edkins S; Estrada K; Evans DM; Farrall M; Ferrario MM; Ferrières J; Franke L; Frau F; Gejman PV; Grallert H; Grönberg H; Gudnason V; Hall AS; Hall P; Hartikainen AL; Hayward C; Heard-Costa NL; Heath AC; Hebebrand J; Homuth G; Hu FB; Hunt SE; Hyppönen E; Iribarren C; Jacobs KB; Jansson JO; Jula A; Kähönen M; Kathiresan S; Kee F; Khaw KT; Kivimäki M; Koenig W; Kraja AT; Kumari M; Kuulasmaa K; Kuusisto J; Laitinen JH; Lakka TA; Langenberg C; Launer LJ; Lind L; Lindström J; Liu J; Liuzzi A; Lokki ML; Lorentzon M; Madden PA; Magnusson PK; Manunta P; Marek D; März W; Mateo Leach I; McKnight B; Medland SE; Mihailov E; Milani L; Montgomery GW; Mooser V; Mühleisen TW; Munroe PB; Musk AW; Narisu N; Navis G; Nicholson G; Nohr EA; Ong KK; Oostra BA; Palmer CN; Palotie A; Peden JF; Pedersen N; Peters A; Polasek O; Pouta A; Pramstaller PP; Prokopenko I; Pütter C; Radhakrishnan A; Raitakari O; Rendon A; Rivadeneira F; Rudan I; Saaristo TE; Sambrook JG; Sanders AR; Sanna S; Saramies J; Schipf S; Schreiber S; Schunkert H; Shin SY; Signorini S; Sinisalo J; Skrobek B; Soranzo N; Stancáková A; Stark K; Stephens JC; Stirrups K; Stolk RP; Stumvoll M; Swift AJ; Theodoraki EV; Thorand B; Tregouet DA; Tremoli E; van der Klauw MM; van Meurs JB; Vermeulen SH; Viikari J; Virtamo J; Vitart V; Waeber G; Wang Z; Widén E; Wild SH; Willemsen G; Winkelmann BR; Witteman JC; Wolffenbuttel BH; Wong A; Wright AF; Zillikens MC; Amouyel P; Boehm BO; Boerwinkle E; Boomsma DI; Caulfield MJ; Chanock SJ; Cupples LA; Cusi D; Dedoussis GV; Erdmann J; Eriksson JG; Franks PW; Froguel P; Gieger C; Gyllensten U; Hamsten A; Harris TB; Hengstenberg C; Hicks AA; Hingorani A; Hinney A; Hofman A; Hovingh KG; Hveem K; Illig T; Jarvelin MR; Jöckel KH; Keinanen-Kiukaanniemi SM; Kiemeney LA; Kuh D; Laakso M; Lehtimäki T; Levinson DF; Martin NG; Metspalu A; Morris AD; Nieminen MS; Njølstad I; Ohlsson C; Oldehinkel AJ; Ouwehand WH; Palmer LJ; Penninx B; Power C; Province MA; Psaty BM; Qi L; Rauramaa R; Ridker PM; Ripatti S; Salomaa V; Samani NJ; Snieder H; Sørensen TI; Spector TD; Stefansson K; Tönjes A; Tuomilehto J; Uitterlinden AG; Uusitupa M; van der Harst P; Vollenweider P; Wallaschofski H; Wareham NJ; Watkins H; Wichmann HE; Wilson JF; Abecasis GR; Assimes TL; Barroso I; Boehnke M; Borecki IB; Deloukas P; Fox CS; Frayling T; Groop LC; Haritunian T; Heid IM; Hunter D; Kaplan RC; Karpe F; Moffatt MF; Mohlke KL; O'Connell JR; Pawitan Y; Schadt EE; Schlessinger D; Steinthorsdottir V; Strachan DP; Thorsteinsdottir U; van Duijn CM; Visscher PM; Di Blasio AM; Hirschhorn JN; Lindgren CM; Morris AP; Meyre D; Scherag A; McCarthy MI; Speliotes EK; North KE; Loos RJ; Ingelsson E (2013)
      Approaches exploiting trait distribution extremes may be used to identify loci associated with common traits, but it is unknown whether these loci are generalizable to the broader population. In a genome-wide search for ...
    • The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study 

      Winkler TW; Justice AE; Graff M; Barata L; Feitosa MF; Chu S; Czajkowski J; Esko T; Fall T; Kilpeläinen TO; Lu Y; Mägi R; Mihailov E; Pers TH; Rüeger S; Teumer A; Ehret GB; Ferreira T; Heard-Costa NL; Karjalainen J; Lagou V; Mahajan A; Neinast MD; Prokopenko I; Simino J; Teslovich TM; Jansen R; Westra HJ; White CC; Absher D; Ahluwalia TS; Ahmad S; Albrecht E; Alves AC; Bragg-Gresham JL; de Craen AJ; Bis JC; Bonnefond A; Boucher G; Cadby G; Cheng YC; Chiang CW; Delgado G; Demirkan A; Dueker N; Eklund N; Eiriksdottir G; Eriksson J; Feenstra B; Fischer K; Frau F; Galesloot TE; Geller F; Goel A; Gorski M; Grammer TB; Gustafsson S; Haitjema S; Hottenga JJ; Huffman JE; Jackson AU; Jacobs KB; Johansson Å; Kaakinen M; Kleber ME; Lahti J; Mateo Leach I; Lehne B; Liu Y; Lo KS; Lorentzon M; Luan J; Madden PA; Mangino M; McKnight B; Medina-Gomez C; Monda KL; Montasser ME; Müller G; Müller-Nurasyid M; Nolte IM; Panoutsopoulou K; Pascoe L; Paternoster L; Rayner NW; Renström F; Rizzi F; Rose LM; Ryan KA; Salo P; Sanna S; Scharnagl H; Shi J; Smith AV; Southam L; Stančáková A; Steinthorsdottir V; Strawbridge RJ; Sung YJ; Tachmazidou I; Tanaka T; Thorleifsson G; Trompet S; Pervjakova N; Tyrer JP; Vandenput L; van der Laan SW; van der Velde N; van Setten J; van Vliet-Ostaptchouk JV; Verweij N; Vlachopoulou E; Waite LL; Wang SR; Wang Z; Wild SH; Willenborg C; Wilson JF; Wong A; Yang J; Yengo L; Yerges-Armstrong LM; Yu L; Zhang W; Zhao JH; Andersson EA; Bakker SJ; Baldassarre D; Banasik K; Barcella M; Barlassina C; Bellis C; Benaglio P; Blangero J; Blüher M; Bonnet F; Bonnycastle LL; Boyd HA; Bruinenberg M; Buchman AS; Campbell H; Chen YD; Chines PS; Claudi-Boehm S; Cole J; Collins FS; de Geus EJ; de Groot LC; Dimitriou M; Duan J; Enroth S; Eury E; Farmaki AE; Forouhi NG; Friedrich N; Gejman PV; Gigante B; Glorioso N; Go AS; Gottesman O; Gräßler J; Grallert H; Grarup N; Gu YM; Broer L; Ham AC; Hansen T; Harris TB; Hartman CA; Hassinen M; Hastie N; Hattersley AT; Heath AC; Henders AK; Hernandez D; Hillege H; Holmen O; Hovingh KG; Hui J; Husemoen LL; Hutri-Kähönen N; Hysi PG; Illig T; De Jager PL; Jalilzadeh S; Jørgensen T; Jukema JW; Juonala M; Kanoni S; Karaleftheri M; Khaw KT; Kinnunen L; Kittner SJ; Koenig W; Kolcic I; Kovacs P; Krarup NT; Kratzer W; Krüger J; Kuh D; Kumari M; Kyriakou T; Langenberg C; Lannfelt L; Lanzani C; Lotay V; Launer LJ; Leander K; Lindström J; Linneberg A; Liu YP; Lobbens S; Luben R; Lyssenko V; Männistö S; Magnusson PK; McArdle WL; Menni C; Merger S; Milani L; Montgomery GW; Morris AP; Narisu N; Nelis M; Ong KK; Palotie A; Pérusse L; Pichler I; Pilia MG; Pouta A; Rheinberger M; Ribel-Madsen R; Richards M; Rice KM; Rice TK; Rivolta C; Salomaa V; Sanders AR; Sarzynski MA; Scholtens S; Scott RA; Scott WR; Sebert S; Sengupta S; Sennblad B; Seufferlein T; Silveira A; Slagboom PE; Smit JH; Sparsø TH; Stirrups K; Stolk RP; Stringham HM; Swertz MA; Swift AJ; Syvänen AC; Tan ST; Thorand B; Tönjes A; Tremblay A; Tsafantakis E; van der Most PJ; Völker U; Vohl MC; Vonk JM; Waldenberger M; Walker RW; Wennauer R; Widén E; Willemsen G; Wilsgaard T; Wright AF; Zillikens MC; van Dijk SC; van Schoor NM; Asselbergs FW; de Bakker PI; Beckmann JS; Beilby J; Bennett DA; Bergman RN; Bergmann S; Böger CA; Boehm BO; Boerwinkle E; Boomsma DI; Bornstein SR; Bottinger EP; Bouchard C; Chambers JC; Chanock SJ; Chasman DI; Cucca F; Cusi D; Dedoussis G; Erdmann J; Eriksson JG; Evans DA; de Faire U; Farrall M; Ferrucci L; Ford I; Franke L; Franks PW; Froguel P; Gansevoort RT; Gieger C; Grönberg H; Gudnason V; Gyllensten U; Hall P; Hamsten A; van der Harst P; Hayward C; Heliövaara M; Hengstenberg C; Hicks AA; Hingorani A; Hofman A; Hu F; Huikuri HV; Hveem K; James AL; Jordan JM; Jula A; Kähönen M; Kajantie E; Kathiresan S; Kiemeney LA; Kivimaki M; Knekt PB; Koistinen HA; Kooner JS; Koskinen S; Kuusisto J; Maerz W; Martin NG; Laakso M; Lakka TA; Lehtimäki T; Lettre G; Levinson DF; Lind L; Lokki ML; Mäntyselkä P; Melbye M; Metspalu A; Mitchell BD; Moll FL; Murray JC; Musk AW; Nieminen MS; Njølstad I; Ohlsson C; Oldehinkel AJ; Oostra BA; Palmer LJ; Pankow JS; Pasterkamp G; Pedersen NL; Pedersen O; Penninx BW; Perola M; Peters A; Polašek O; Pramstaller PP; Psaty BM; Qi L; Quertermous T; Raitakari OT; Rankinen T; Rauramaa R; Ridker PM; Rioux JD; Rivadeneira F; Rotter JI; Rudan I; den Ruijter HM; Saltevo J; Sattar N; Schunkert H; Schwarz PE; Shuldiner AR; Sinisalo J; Snieder H; Sørensen TI; Spector TD; Staessen JA; Stefania B; Thorsteinsdottir U; Stumvoll M; Tardif JC; Tremoli E; Tuomilehto J; Uitterlinden AG; Uusitupa M; Verbeek AL; Vermeulen SH; Viikari JS; Vitart V; Völzke H; Vollenweider P; Waeber G; Walker M; Wallaschofski H; Wareham NJ; Watkins H; Zeggini E; CHARGE Consortium; DIAGRAM Consortium; GLGC Consortium; Global-BPGen Consortium; ICBP Consortium; MAGIC Consortium; Chakravarti A; Clegg DJ; Cupples LA; Gordon-Larsen P; Jaquish CE; Rao DC; Abecasis GR; Assimes TL; Barroso I; Berndt SI; Boehnke M; Deloukas P; Fox CS; Groop LC; Hunter DJ; Ingelsson E; Kaplan RC; McCarthy MI; Mohlke KL; O'Connell JR; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Hirschhorn JN; Lindgren CM; Heid IM; North KE; Borecki IB; Kutalik Z; Loos RJ (2015)
      Genome-wide association studies (GWAS) have identified more than 100 genetic variants contributing to BMI, a measure of body size, or waist-to-hip ratio (adjusted for BMI, WHRadjBMI), a measure of body shape. Body size and ...
    • Large-scale association analyses identify new loci influencing glycemic traits and provide insight into the underlying biological pathways 

      Scott RA; Lagou V; Welch RP; Wheeler E; Montasser ME; Luan J; Mägi R; Strawbridge RJ; Rehnberg E; Gustafsson S; Kanoni S; Rasmussen-Torvik LJ; Yengo L; Lecoeur C; Shungin D; Sanna S; Sidore C; Johnson PC; Jukema JW; Johnson T; Mahajan A; Verweij N; Thorleifsson G; Hottenga JJ; Shah S; Smith AV; Sennblad B; Gieger C; Salo P; Perola M; Timpson NJ; Evans DM; Pourcain BS; Wu Y; Andrews JS; Hui J; Bielak LF; Zhao W; Horikoshi M; Navarro P; Isaacs A; O'Connell JR; Stirrups K; Vitart V; Hayward C; Esko T; Mihailov E; Fraser RM; Fall T; Voight BF; Raychaudhuri S; Chen H; Lindgren CM; Morris AP; Rayner NW; Robertson N; Rybin D; Liu CT; Beckmann JS; Willems SM; Chines PS; Jackson AU; Kang HM; Stringham HM; Song K; Tanaka T; Peden JF; Goel A; Hicks AA; An P; Müller-Nurasyid M; Franco-Cereceda A; Folkersen L; Marullo L; Jansen H; Oldehinkel AJ; Bruinenberg M; Pankow JS; North KE; Forouhi NG; Loos RJ; Edkins S; Varga TV; Hallmans G; Oksa H; Antonella M; Nagaraja R; Trompet S; Ford I; Bakker SJ; Kong A; Kumari M; Gigante B; Herder C; Munroe PB; Caulfield M; Antti J; Mangino M; Small K; Miljkovic I; Liu Y; Atalay M; Kiess W; James AL; Rivadeneira F; Uitterlinden AG; Palmer CN; Doney AS; Willemsen G; Smit JH; Campbell S; Polasek O; Bonnycastle LL; Hercberg S; Dimitriou M; Bolton JL; Fowkes GR; Kovacs P; Lindström J; Zemunik T; Bandinelli S; Wild SH; Basart HV; Rathmann W; Grallert H; DIAGRAM Consortium; Maerz W; Kleber ME; Boehm BO; Peters A; Pramstaller PP; Province MA; Borecki IB; Hastie ND; Rudan I; Campbell H; Watkins H; Farrall M; Stumvoll M; Ferrucci L; Waterworth DM; Bergman RN; Collins FS; Tuomilehto J; Watanabe RM; de Geus EJ; Penninx BW; Hofman A; Oostra BA; Psaty BM; Vollenweider P; Wilson JF; Wright AF; Hovingh GK; Metspalu A; Uusitupa M; Magnusson PK; Kyvik KO; Kaprio J; Price JF; Dedoussis GV; Deloukas P; Meneton P; Lind L; Boehnke M; Shuldiner AR; van Duijn CM; Morris AD; Toenjes A; Peyser PA; Beilby JP; Körner A; Kuusisto J; Laakso M; Bornstein SR; Schwarz PE; Lakka TA; Rauramaa R; Adair LS; Smith GD; Spector TD; Illig T; de Faire U; Hamsten A; Gudnason V; Kivimaki M; Hingorani A; Keinanen-Kiukaanniemi SM; Saaristo TE; Boomsma DI; Stefansson K; van der Harst P; Dupuis J; Pedersen NL; Sattar N; Harris TB; Cucca F; Ripatti S; Salomaa V; Mohlke KL; Balkau B; Froguel P; Pouta A; Jarvelin MR; Wareham NJ; Bouatia-Naji N; McCarthy MI; Franks PW; Meigs JB; Teslovich TM; Florez JC; Langenberg C; Ingelsson E; Prokopenko I; Barroso I (2012)
      Through genome-wide association meta-analyses of up to 133,010 individuals of European ancestry without diabetes, including individuals newly genotyped using the Metabochip, we have increased the number of confirmed loci ...
    • New genetic loci link adipose and insulin biology to body fat distribution 

      Shungin D; Winkler TW; Croteau-Chonka DC; Ferreira T; Locke AE; Mägi R; Strawbridge RJ; Pers TH; Fischer K; Justice AE; Workalemahu T; Wu JM; Buchkovich ML; Heard-Costa NL; Roman TS; Drong AW; Song C; Gustafsson S; Day FR; Esko T; Fall T; Kutalik Z; Luan J; Randall JC; Scherag A; Vedantam S; Wood AR; Chen J; Fehrmann R; Karjalainen J; Kahali B; Liu CT; Schmidt EM; Absher D; Amin N; Anderson D; Beekman M; Bragg-Gresham JL; Buyske S; Demirkan A; Ehret GB; Feitosa MF; Goel A; Jackson AU; Johnson T; Kleber ME; Kristiansson K; Mangino M; Mateo Leach I; Medina-Gomez C; Palmer CD; Pasko D; Pechlivanis S; Peters MJ; Prokopenko I; Stančáková A; Ju Sung Y; Tanaka T; Teumer A; van Vliet-Ostaptchouk JV; Yengo L; Zhang W; Albrecht E; Ärnlöv J; Arscott GM; Bandinelli S; Barrett A; Bellis C; Bennett AJ; Berne C; Blüher M; Böhringer S; Bonnet F; Böttcher Y; Bruinenberg M; Carba DB; Caspersen IH; Clarke R; Daw EW; Deelen J; Deelman E; Delgado G; Doney AS; Eklund N; Erdos MR; Estrada K; Eury E; Friedrich N; Garcia ME; Giedraitis V; Gigante B; Go AS; Golay A; Grallert H; Grammer TB; Gräßler J; Grewal J; Groves CJ; Haller T; Hallmans G; Hartman CA; Hassinen M; Hayward C; Heikkilä K; Herzig KH; Helmer Q; Hillege HL; Holmen O; Hunt SC; Isaacs A; Ittermann T; James AL; Johansson I; Juliusdottir T; Kalafati IP; Kinnunen L; Koenig W; Kooner IK; Kratzer W; Lamina C; Leander K; Lee NR; Lichtner P; Lind L; Lindström J; Lobbens S; Lorentzon M; Mach F; Magnusson PK; Mahajan A; McArdle WL; Menni C; Merger S; Mihailov E; Milani L; Mills R; Moayyeri A; Monda KL; Mooijaart SP; Mühleisen TW; Mulas A; Müller G; Müller-Nurasyid M; Nagaraja R; Nalls MA; Narisu N; Glorioso N; Nolte IM; Olden M; Rayner NW; Renstrom F; Ried JS; Robertson NR; Rose LM; Sanna S; Scharnagl H; Scholtens S; Sennblad B; Seufferlein T; Sitlani CM; Vernon Smith A; Stirrups K; Stringham HM; Sundström J; Swertz MA; Swift AJ; Syvänen AC; Tayo BO; Thorand B; Thorleifsson G; Tomaschitz A; Troffa C; van Oort FV; Verweij N; Vonk JM; Waite LL; Wennauer R; Wilsgaard T; Wojczynski MK; Wong A; Zhang Q; Hua Zhao J; Brennan EP; Choi M; Eriksson P; Folkersen L; Franco-Cereceda A; Gharavi AG; Hedman ÅK; Hivert MF; Huang J; Kanoni S; Karpe F; Keildson S; Kiryluk K; Liang L; Lifton RP; Ma B; McKnight AJ; McPherson R; Metspalu A; Min JL; Moffatt MF; Montgomery GW; Murabito JM; Nicholson G; Nyholt DR; Olsson C; Perry JR; Reinmaa E; Salem RM; Sandholm N; Schadt EE; Scott RA; Stolk L; Vallejo EE; Westra HJ; Zondervan KT; ADIPOGen Consortium; CARDIOGRAMplusC4D Consortium; CKDGen Consortium; GEFOS Consortium; GENIE Consortium; GLGC; ICBP; International Endogene Consortium; LifeLines Cohort Study; MAGIC Investigators; MuTHER Consortium; PAGE Consortium; ReproGen Consortium; Amouyel P; Arveiler D; Bakker SJ; Beilby J; Bergman RN; Blangero J; Brown MJ; Burnier M; Campbell H; Chakravarti A; Chines PS; Claudi-Boehm S; Collins FS; Crawford DC; Danesh J; de Faire U; de Geus EJ; Dörr M; Erbel R; Eriksson JG; Farrall M; Ferrannini E; Ferrières J; Forouhi NG; Forrester T; Franco OH; Gansevoort RT; Gieger C; Gudnason V; Haiman CA; Harris TB; Hattersley AT; Heliövaara M; Hicks AA; Hingorani AD; Hoffmann W; Hofman A; Homuth G; Humphries SE; Hyppönen E; Illig T; Jarvelin MR; Johansen B; Jousilahti P; Jula AM; Kaprio J; Kee F; Keinanen-Kiukaanniemi SM; Kooner JS; Kooperberg C; Kovacs P; Kraja AT; Kumari M; Kuulasmaa K; Kuusisto J; Lakka TA; Langenberg C; Le Marchand L; Lehtimäki T; Lyssenko V; Männistö S; Marette A; Matise TC; McKenzie CA; McKnight B; Musk AW; Möhlenkamp S; Morris AD; Nelis M; Ohlsson C; Oldehinkel AJ; Ong KK; Palmer LJ; Penninx BW; Peters A; Pramstaller PP; Raitakari OT; Rankinen T; Rao DC; Rice TK; Ridker PM; Ritchie MD; Rudan I; Salomaa V; Samani NJ; Saramies J; Sarzynski MA; Schwarz PE; Shuldiner AR; Staessen JA; Steinthorsdottir V; Stolk RP; Strauch K; Tönjes A; Tremblay A; Tremoli E; Vohl MC; Völker U; Vollenweider P; Wilson JF; Witteman JC; Adair LS; Bochud M; Boehm BO; Bornstein SR; Bouchard C; Cauchi S; Caulfield MJ; Chambers JC; Chasman DI; Cooper RS; Dedoussis G; Ferrucci L; Froguel P; Grabe HJ; Hamsten A; Hui J; Hveem K; Jöckel KH; Kivimaki M; Kuh D; Laakso M; Liu Y; März W; Munroe PB; Njølstad I; Oostra BA; Palmer CN; Pedersen NL; Perola M; Pérusse L; Peters U; Power C; Quertermous T; Rauramaa R; Rivadeneira F; Saaristo TE; Saleheen D; Sinisalo J; Slagboom PE; Snieder H; Spector TD; Thorsteinsdottir U; Stumvoll M; Tuomilehto J; Uitterlinden AG; Uusitupa M; van der Harst P; Veronesi G; Walker M; Wareham NJ; Watkins H; Wichmann HE; Abecasis GR; Assimes TL; Berndt SI; Boehnke M; Borecki IB; Deloukas P; Franke L; Frayling TM; Groop LC; Hunter DJ; Kaplan RC; O'Connell JR; Qi L; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Willer CJ; Visscher PM; Yang J; Hirschhorn JN; Zillikens MC; McCarthy MI; Speliotes EK; North KE; Fox CS; Barroso I; Franks PW; Ingelsson E; Heid IM; Loos RJ; Cupples LA; Morris AP; Lindgren CM; Mohlke KL (2015)
      Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and ...
    • Quality control and conduct of genome-wide association meta-analyses 

      Winkler TW; Day FR; Croteau-Chonka DC; Wood AR; Locke AE; Mägi R; Ferreira T; Fall T; Graff M; Justice AE; Luan J; Gustafsson S; Randall JC; Vedantam S; Workalemahu T; Kilpeläinen TO; Scherag A; Esko T; Kutalik Z; Heid IM; Loos RJ; Genetic Investigation of Anthropometric Traits (GIANT) Consortium (2014)
      Rigorous organization and quality control (QC) are necessary to facilitate successful genome-wide association meta-analyses (GWAMAs) of statistics aggregated across multiple genome-wide association studies. This protocol ...
    • Sex-stratified genome-wide association studies including 270,000 individuals show sexual dimorphism in genetic loci for anthropometric traits 

      Randall JC; Winkler TW; Kutalik Z; Berndt SI; Jackson AU; Monda KL; Kilpeläinen TO; Esko T; Mägi R; Li S; Workalemahu T; Feitosa MF; Croteau-Chonka DC; Day FR; Fall T; Ferreira T; Gustafsson S; Locke AE; Mathieson I; Scherag A; Vedantam S; Wood AR; Liang L; Steinthorsdottir V; Thorleifsson G; Dermitzakis ET; Dimas AS; Karpe F; Min JL; Nicholson G; Clegg DJ; Person T; Krohn JP; Bauer S; Buechler C; Eisinger K; DIAGRAM Consortium; Bonnefond A; Froguel P; MAGIC Investigators; Hottenga JJ; Prokopenko I; Waite LL; Harris TB; Smith AV; Shuldiner AR; McArdle WL; Caulfield MJ; Munroe PB; Grönberg H; Chen YD; Li G; Beckmann JS; Johnson T; Thorsteinsdottir U; Teder-Laving M; Khaw KT; Wareham NJ; Zhao JH; Amin N; Oostra BA; Kraja AT; Province MA; Cupples LA; Heard-Costa NL; Kaprio J; Ripatti S; Surakka I; Collins FS; Saramies J; Tuomilehto J; Jula A; Salomaa V; Erdmann J; Hengstenberg C; Loley C; Schunkert H; Lamina C; Wichmann HE; Albrecht E; Gieger C; Hicks AA; Johansson A; Pramstaller PP; Kathiresan S; Speliotes EK; Penninx B; Hartikainen AL; Jarvelin MR; Gyllensten U; Boomsma DI; Campbell H; Wilson JF; Chanock SJ; Farrall M; Goel A; Medina-Gomez C; Rivadeneira F; Estrada K; Uitterlinden AG; Hofman A; Zillikens MC; den Heijer M; Kiemeney LA; Maschio A; Hall P; Tyrer J; Teumer A; Völzke H; Kovacs P; Tönjes A; Mangino M; Spector TD; Hayward C; Rudan I; Hall AS; Samani NJ; Attwood AP; Sambrook JG; Hung J; Palmer LJ; Lokki ML; Sinisalo J; Boucher G; Huikuri H; Lorentzon M; Ohlsson C; Eklund N; Eriksson JG; Barlassina C; Rivolta C; Nolte IM; Snieder H; van der Klauw MM; van Vliet-Ostaptchouk JV; Gejman PV; Shi J; Jacobs KB; Wang Z; Bakker SJ; Mateo Leach I; Navis G; van der Harst P; Martin NG; Medland SE; Montgomery GW; Yang J; Chasman DI; Ridker PM; Rose LM; Lehtimäki T; Raitakari O; Absher D; Iribarren C; Basart H; Hovingh KG; Hyppönen E; Power C; Anderson D; Beilby JP; Hui J; Jolley J; Sager H; Bornstein SR; Schwarz PE; Kristiansson K; Perola M; Lindström J; Swift AJ; Uusitupa M; Atalay M; Lakka TA; Rauramaa R; Bolton JL; Fowkes G; Fraser RM; Price JF; Fischer K; Krjutå Kov K; Metspalu A; Mihailov E; Langenberg C; Luan J; Ong KK; Chines PS; Keinanen-Kiukaanniemi SM; Saaristo TE; Edkins S; Franks PW; Hallmans G; Shungin D; Morris AD; Palmer CN; Erbel R; Moebus S; Nöthen MM; Pechlivanis S; Hveem K; Narisu N; Hamsten A; Humphries SE; Strawbridge RJ; Tremoli E; Grallert H; Thorand B; Illig T; Koenig W; Müller-Nurasyid M; Peters A; Boehm BO; Kleber ME; März W; Winkelmann BR; Kuusisto J; Laakso M; Arveiler D; Cesana G; Kuulasmaa K; Virtamo J; Yarnell JW; Kuh D; Wong A; Lind L; de Faire U; Gigante B; Magnusson PK; Pedersen NL; Dedoussis G; Dimitriou M; Kolovou G; Kanoni S; Stirrups K; Bonnycastle LL; Njølstad I; Wilsgaard T; Ganna A; Rehnberg E; Hingorani A; Kivimaki M; Kumari M; Assimes TL; Barroso I; Boehnke M; Borecki IB; Deloukas P; Fox CS; Frayling T; Groop LC; Haritunians T; Hunter D; Ingelsson E; Kaplan R; Mohlke KL; O'Connell JR; Schlessinger D; Strachan DP; Stefansson K; van Duijn CM; Abecasis GR; McCarthy MI; Hirschhorn JN; Qi L; Loos RJ; Lindgren CM; North KE; Heid IM (2013)
      Given the anthropometric differences between men and women and previous evidence of sex-difference in genetic effects, we conducted a genome-wide search for sexually dimorphic associations with height, weight, body mass ...