Now showing items 1-5 of 5

    • Jenti: an efficient tool for mining complex inbred genealogies 

      Falchi M; Fuchsberger C (2008)
      SUMMARY: An efficient tool for mining complex inbred genealogies that identify clusters of individuals sharing the same expected amount of relatedness is described. Additionally it allows for the reconstruction of ...
    • Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts 

      Aulchenko YS; Ripatti S; Lindqvist I; Boomsma D; Heid IM; Pramstaller PP; Penninx BW; Janssens AC; Wilson JF; Spector T; Martin NG; Pedersen NL; Kyvik KO; Kaprio J; Hofman A; Freimer NB; Jarvelin MR; Gyllensten U; Campbell H; Rudan I; Johansson A; Marroni F; Hayward C; Vitart V; Jonasson I; Pattaro C; Wright A; Hastie N; Pichler I; Hicks AA; Falchi M; Willemsen G; Hottenga JJ; de Geus EJ; Montgomery GW; Whitfield J; Magnusson P; Saharinen J; Perola M; Silander K; Isaacs A; Sijbrands EJ; Uitterlinden AG; Witteman JC; Oostra BA; Elliott P; Ruokonen A; Sabatti C; Gieger C; Meitinger T; Kronenberg F; Döring A; Wichmann HE; Smit JH; McCarthy MI; van Duijn CM; Peltonen L; ENGAGE Consortium (2009)
      Recent genome-wide association (GWA) studies of lipids have been conducted in samples ascertained for other phenotypes, particularly diabetes. Here we report the first GWA analysis of loci affecting total cholesterol (TC), ...
    • Low-frequency variants in HMGA1 are not associated with type 2 diabetes risk 

      Marquez M; Huyvaert M; Perry JR; Pearson RD; Falchi M; Morris AP; Vivequin S; Lobbens S; Yengo L; Gaget S; Pattou F; Poulain-Godefroy O; Charpentier G; Carlsson LM; Jacobson P; Sjöström L; Lantieri O; Heude B; Walley A; Balkau B; Marre M; Froguel P; Cauchi S; DIAGRAM Consortium (2012)
      It has recently been suggested that the low-frequency c.136-14_136-13insC variant in high-mobility group A1 (HMGA1) may strongly contribute to insulin resistance and type 2 diabetes risk. In our study, we attempted to ...
    • New gene functions in megakaryopoiesis and platelet formation 

      Gieger C; Radhakrishnan A; Cvejic A; Tang W; Porcu E; Pistis G; Serbanovic-Canic J; Elling U; Goodall AH; Labrune Y; Lopez LM; Mägi R; Meacham S; Okada Y; Pirastu N; Sorice R; Teumer A; Voss K; Zhang W; Ramirez-Solis R; Bis JC; Ellinghaus D; Gögele M; Hottenga JJ; Langenberg C; Kovacs P; O'Reilly PF; Shin SY; Esko T; Hartiala J; Kanoni S; Murgia F; Parsa A; Stephens J; van der Harst P; Ellen van der Schoot C; Allayee H; Attwood A; Balkau B; Bastardot F; Basu S; Baumeister SE; Biino G; Bomba L; Bonnefond A; Cambien F; Chambers JC; Cucca F; D'Adamo P; Davies G; de Boer RA; de Geus EJ; Döring A; Elliott P; Erdmann J; Evans DM; Falchi M; Feng W; Folsom AR; Frazer IH; Gibson QD; Glazer NL; Hammond C; Hartikainen AL; Heckbert SR; Hengstenberg C; Hersch M; Illig T; Loos RJ; Jolley J; Khaw KT; Kühnel B; Kyrtsonis MC; Lagou V; Lloyd-Jones H; Lumley T; Mangino M; Maschio A; Mateo Leach I; McKnight B; Memari Y; Mitchell BD; Montgomery GW; Nakamura Y; Nauck M; Navis G; Nöthlings U; Nolte IM; Porteous DJ; Pouta A; Pramstaller PP; Pullat J; Ring SM; Rotter JI; Ruggiero D; Ruokonen A; Sala C; Samani NJ; Sambrook J; Schlessinger D; Schreiber S; Schunkert H; Scott J; Smith NL; Snieder H; Starr JM; Stumvoll M; Takahashi A; Tang WH; Taylor K; Tenesa A; Lay Thein S; Tönjes A; Uda M; Ulivi S; van Veldhuisen DJ; Visscher PM; Völker U; Wichmann HE; Wiggins KL; Willemsen G; Yang TP; Hua Zhao J; Zitting P; Bradley JR; Dedoussis GV; Gasparini P; Hazen SL; Metspalu A; Pirastu M; Shuldiner AR; Joost van Pelt L; Zwaginga JJ; Boomsma DI; Deary IJ; Franke A; Froguel P; Ganesh SK; Jarvelin MR; Martin NG; Meisinger C; Psaty BM; Spector TD; Wareham NJ; Akkerman JW; Ciullo M; Deloukas P; Greinacher A; Jupe S; Kamatani N; Khadake J; Kooner JS; Penninger J; Prokopenko I; Stemple D; Toniolo D; Wernisch L; Sanna S; Hicks AA; Rendon A; Ferreira MA; Ouwehand WH; Soranzo N (2011)
      Platelets are the second most abundant cell type in blood and are essential for maintaining haemostasis. Their count and volume are tightly controlled within narrow physiological ranges, but there is only limited understanding ...
    • PedVizApi: a Java API for the interactive, visual analysis of extended pedigrees 

      Fuchsberger C; Falchi M; Forer L; Pramstaller PP (2008)
      PedVizApi is a Java API (application program interface) for the visual analysis of large and complex pedigrees. It provides all the necessary functionality for the interactive exploration of extended genealogies. While ...