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Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
(2009)Recent genome-wide association (GWA) studies of lipids have been conducted in samples ascertained for other phenotypes, particularly diabetes. Here we report the first GWA analysis of loci affecting total cholesterol (TC), ... -
Common variants in the JAZF1 gene associated with height identified by linkage and genome-wide association analysis
(2009)Genes for height have gained interest for decades, but only recently have candidate genes started to be identified. We have performed linkage analysis and genome-wide association for height in approximately 4000 individuals ... -
Common variants at ten loci modulate the QT interval duration in the QTSCD Study
(2009)The QT interval, a measure of cardiac repolarization, predisposes to ventricular arrhythmias and sudden cardiac death (SCD) when prolonged or shortened. A common variant in NOS1AP is known to influence repolarization. We ... -
ParkScreen: a low-cost rapid linkage marker panel for Parkinson's disease
(2009)A genetic marker screening panel, ParkScreen, optimized for simultaneous marker amplification, was constructed to test or exclude linkage in families with parkinsonism or Parkinson's disease, using only a few affected ... -
Genome-wide linkage analysis of serum creatinine in three isolated European populations
(2009)There is increasing evidence for a role of genetic predisposition in the etiology of kidney disease, but linkage scans have been poorly replicated. Here we performed a genome-wide linkage analysis of serum creatinine on ...