Search

Now showing items 1-6 of 6

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

Dehghan A; Dupuis J; Barbalic M; Bis JC; Eiriksdottir G; Lu C; Pellikka N; Wallaschofski H; Kettunen J; Henneman P; Baumert J; Strachan DP; Fuchsberger C; Vitart V; Wilson JF; Paré G; Naitza S; Rudock ME; Surakka I; de Geus EJ; Alizadeh BZ; Guralnik J; Shuldiner A; Tanaka T; Zee RY; Schnabel RB; Nambi V; Kavousi M; Ripatti S; Nauck M; Smith NL; Smith AV; Sundvall J; Scheet P; Liu Y; Ruokonen A; Rose LM; Larson MG; Hoogeveen RC; Freimer NB; Teumer A; Tracy RP; Launer LJ; Buring JE; Yamamoto JF; Folsom AR; Sijbrands EJ; Pankow J; Elliott P; Keaney JF; Sun W; Sarin AP; Fontes JD; Badola S; Astor BC; Hofman A; Pouta A; Werdan K; Greiser KH; Kuss O; Meyer Zu Schwabedissen H; Thiery J; Jamshidi Y; Nolte IM; Soranzo N; Spector TD; Völzke H; Parker AN; Aspelund T; Bates D; Young L; Tsui K; Siscovick DS; Guo X; Rotter JI; Uda M; Schlessinger D; Rudan I; Hicks AA; Penninx BW; Thorand B; Gieger C; Coresh J; Willemsen G; Harris TB; Uitterlinden AG; Järvelin MR; Rice K; Radke D; Salomaa V; Willems van Dijk K; Boerwinkle E; Vasan RS; Ferrucci L; Gibson QD; Bandinelli S; Snieder H; Boomsma DI; Xiao X; Campbell H; Hayward C; Pramstaller PP; van Duijn CM; Peltonen L; Psaty BM; Gudnason V; Ridker PM; Homuth G; Koenig W; Ballantyne CM; Witteman JC; Benjamin EJ; Perola M; Chasman DI (2011)
BACKGROUND: C-reactive protein (CRP) is a heritable marker of chronic inflammation that is strongly associated with cardiovascular disease. We sought to identify genetic variants that are associated with CRP levels. METHODS ...
Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

Oexle K; Ried JS; Hicks AA; Tanaka T; Hayward C; Bruegel M; Gögele M; Lichtner P; Müller-Myhsok B; Döring A; Illig T; Schwienbacher C; Minelli C; Pichler I; Fiedler GM; Thiery J; Rudan I; Wright AF; Campbell H; Ferrucci L; Bandinelli S; Pramstaller PP; Wichmann HE; Gieger C; Winkelmann J; Meitinger T (2011)
The level of body iron storage and the erythropoietic need for iron are indicated by the serum levels of ferritin and soluble transferrin receptor (sTfR), respectively. A meta-analysis of five genome-wide association studies ...
CUBN is a gene locus for albuminuria

Böger CA; Chen MH; Tin A; Olden M; Köttgen A; de Boer IH; Fuchsberger C; O'Seaghdha CM; Pattaro C; Teumer A; Liu CT; Glazer NL; Li M; O'Connell JR; Tanaka T; Peralta CA; Kutalik Z; Luan J; Zhao JH; Hwang SJ; Akylbekova E; Kramer H; van der Harst P; Smith AV; Lohman K; de Andrade M; Hayward C; Kollerits B; Tönjes A; Aspelund T; Ingelsson E; Eiriksdottir G; Launer LJ; Harris TB; Shuldiner AR; Mitchell BD; Arking DE; Franceschini N; Boerwinkle E; Egan J; Hernandez D; Reilly M; Townsend RR; Lumley T; Siscovick DS; Psaty BM; Kestenbaum B; Haritunians T; Bergmann S; Vollenweider P; Waeber G; Mooser V; Waterworth D; Johnson AD; Florez JC; Meigs JB; Lu X; Turner ST; Atkinson EJ; Leak TS; Aasarød K; Skorpen F; Syvänen AC; Illig T; Baumert J; Koenig W; Krämer BK; Devuyst O; Mychaleckyj JC; Minelli C; Bakker SJ; Kedenko L; Paulweber B; Coassin S; Endlich K; Kroemer HK; Biffar R; Stracke S; Völzke H; Stumvoll M; Mägi R; Campbell H; Vitart V; Hastie ND; Gudnason V; Kardia SL; Liu Y; Polasek O; Curhan G; Kronenberg F; Prokopenko I; Rudan I; Arnlöv J; Hallan S; Navis G; CKDGen Consortium; Parsa A; Ferrucci L; Coresh J; Shlipak MG; Bull SB; Paterson NJ; Wichmann HE; Wareham NJ; Loos RJ; Rotter JI; Pramstaller PP; Cupples LA; Beckmann JS; Yang Q; Heid IM; Rettig R; Dreisbach AW; Bochud M; Fox CS; Kao WH (2011)
Identification of genetic risk factors for albuminuria may alter strategies for early prevention of CKD progression, particularly among patients with diabetes. Little is known about the influence of common genetic variants ...
Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

Oexle K; Ried JS; Hicks AA; Tanaka T; Hayward C; Bruegel M; Gögele M; Lichtner P; Müller-Myhsok B; Döring A; Illig T; Schwienbacher C; Minelli C; Pichler I; Fiedler GM; Thiery J; Rudan I; Wright AF; Campbell H; Ferrucci L; Bandinelli S; Pramstaller PP; Wichmann HE; Gieger C; Winkelmann J; Meitinger T (2011)
The level of body iron storage and the erythropoietic need for iron are indicated by the serum levels of ferritin and soluble transferrin receptor (sTfR), respectively. A meta-analysis of five genome-wide association studies ...
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

International Consortium for Blood Pressure Genome-Wide Association Studies; Ehret GB; Munroe PB; Rice KM; Bochud M; Johnson AD; Chasman DI; Smith AV; Tobin MD; Verwoert GC; Hwang SJ; Pihur V; Vollenweider P; O'Reilly PF; Amin N; Bragg-Gresham JL; Teumer A; Glazer NL; Launer L; Zhao JH; Aulchenko Y; Heath S; Sõber S; Parsa A; Luan J; Arora P; Dehghan A; Zhang F; Lucas G; Hicks AA; Jackson AU; Peden JF; Tanaka T; Wild SH; Rudan I; Igl W; Milaneschi Y; Parker AN; Fava C; Chambers JC; Fox ER; Kumari M; Go MJ; van der Harst P; Kao WH; Sjögren M; Vinay DG; Alexander M; Tabara Y; Shaw-Hawkins S; Whincup PH; Liu Y; Shi G; Kuusisto J; Tayo B; Seielstad M; Sim X; Nguyen KD; Lehtimäki T; Matullo G; Wu Y; Gaunt TR; Onland-Moret NC; Cooper MN; Platou CG; Org E; Hardy R; Dahgam S; Palmen J; Vitart V; Braund PS; Kuznetsova T; Uiterwaal CS; Adeyemo A; Palmas W; Campbell H; Ludwig B; Tomaszewski M; Tzoulaki I; Palmer ND; CARDIoGRAM Consortium; CKDGen Consortium; KidneyGen Consortium; EchoGen consortium; CHARGE-HF consortium; Aspelund T; Garcia M; Chang YP; O'Connell JR; Steinle NI; Grobbee DE; Arking DE; Kardia SL; Morrison AC; Hernandez D; Najjar S; McArdle WL; Hadley D; Brown MJ; Connell JM; Hingorani AD; Day IN; Lawlor DA; Beilby JP; Lawrence RW; Clarke R; Hopewell JC; Ongen H; Dreisbach AW; Li Y; Young JH; Bis JC; Kähönen M; Viikari J; Adair LS; Lee NR; Chen MH; Olden M; Pattaro C; Bolton JA; Köttgen A; Bergmann S; Mooser V; Chaturvedi N; Frayling TM; Islam M; Jafar TH; Erdmann J; Kulkarni SR; Bornstein SR; Grässler J; Groop L; Voight BF; Kettunen J; Howard P; Taylor A; Guarrera S; Ricceri F; Emilsson V; Plump A; Barroso I; Khaw KT; Weder AB; Hunt SC; Sun YV; Bergman RN; Collins FS; Bonnycastle LL; Scott LJ; Stringham HM; Peltonen L; Perola M; Vartiainen E; Brand SM; Staessen JA; Wang TJ; Burton PR; Soler Artigas M; Dong Y; Snieder H; Wang X; Zhu H; Lohman KK; Rudock ME; Heckbert SR; Smith NL; Wiggins KL; Doumatey A; Shriner D; Veldre G; Viigimaa M; Kinra S; Prabhakaran D; Tripathy V; Langefeld CD; Rosengren A; Thelle DS; Corsi AM; Singleton A; Forrester T; Hilton G; McKenzie CA; Salako T; Iwai N; Kita Y; Ogihara T; Ohkubo T; Okamura T; Ueshima H; Umemura S; Eyheramendy S; Meitinger T; Wichmann HE; Cho YS; Kim HL; Lee JY; Scott J; Sehmi JS; Zhang W; Hedblad B; Nilsson P; Smith GD; Wong A; Narisu N; Stancáková A; Raffel LJ; Yao J; Kathiresan S; O'Donnell CJ; Schwartz SM; Ikram MA; Longstreth WT; Mosley TH; Seshadri S; Shrine NR; Wain LV; Morken MA; Swift AJ; Laitinen J; Prokopenko I; Zitting P; Cooper JA; Humphries SE; Danesh J; Rasheed A; Goel A; Hamsten A; Watkins H; Bakker SJ; van Gilst WH; Janipalli CS; Mani KR; Yajnik CS; Hofman A; Mattace-Raso FU; Oostra BA; Demirkan A; Isaacs A; Rivadeneira F; Lakatta EG; Orru M; Scuteri A; Ala-Korpela M; Kangas AJ; Lyytikäinen LP; Soininen P; Tukiainen T; Würtz P; Ong RT; Dörr M; Kroemer HK; Völker U; Völzke H; Galan P; Hercberg S; Lathrop M; Zelenika D; Deloukas P; Mangino M; Spector TD; Zhai G; Meschia JF; Nalls MA; Sharma P; Terzic J; Kumar MV; Denniff M; Zukowska-Szczechowska E; Wagenknecht LE; Fowkes FG; Charchar FJ; Schwarz PE; Hayward C; Guo X; Rotimi C; Bots ML; Brand E; Samani NJ; Polasek O; Talmud PJ; Nyberg F; Kuh D; Laan M; Hveem K; Palmer LJ; van der Schouw YT; Casas JP; Mohlke KL; Vineis P; Raitakari O; Ganesh SK; Wong TY; Tai ES; Cooper RS; Laakso M; Rao DC; Harris TB; Morris RW; Dominiczak AF; Kivimaki M; Marmot MG; Miki T; Saleheen D; Chandak GR; Coresh J; Navis G; Salomaa V; Han BG; Zhu X; Kooner JS; Melander O; Ridker PM; Bandinelli S; Gyllensten UB; Wright AF; Wilson JF; Ferrucci L; Farrall M; Tuomilehto J; Pramstaller PP; Elosua R; Soranzo N; Sijbrands EJ; Altshuler D; Loos RJ; Shuldiner AR; Gieger C; Meneton P; Uitterlinden AG; Wareham NJ; Gudnason V; Rotter JI; Rettig R; Uda M; Strachan DP; Witteman JC; Hartikainen AL; Beckmann JS; Boerwinkle E; Vasan RS; Boehnke M; Larson MG; Järvelin MR; Psaty BM; Abecasis GR; Chakravarti A; Elliott P; van Duijn CM; Newton-Cheh C; Levy D; Caulfield MJ; Johnson T (2011)
Blood pressure is a heritable trait influenced by several biological pathways and responsive to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm Hg systolic blood pressure or ≥90 mm Hg ...
Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure

Wain LV; Verwoert GC; O'Reilly PF; Shi G; Johnson T; Johnson AD; Bochud M; Rice KM; Henneman P; Smith AV; Ehret GB; Amin N; Larson MG; Mooser V; Hadley D; Dörr M; Bis JC; Aspelund T; Esko T; Janssens AC; Zhao JH; Heath S; Laan M; Fu J; Pistis G; Luan J; Arora P; Lucas G; Pirastu N; Pichler I; Jackson AU; Webster RJ; Zhang F; Peden JF; Schmidt H; Tanaka T; Campbell H; Igl W; Milaneschi Y; Hottenga JJ; Vitart V; Chasman DI; Trompet S; Bragg-Gresham JL; Alizadeh BZ; Chambers JC; Guo X; Lehtimäki T; Kühnel B; Lopez LM; Polašek O; Boban M; Nelson CP; Morrison AC; Pihur V; Ganesh SK; Hofman A; Kundu S; Mattace-Raso FU; Rivadeneira F; Sijbrands EJ; Uitterlinden AG; Hwang SJ; Vasan RS; Wang TJ; Bergmann S; Vollenweider P; Waeber G; Laitinen J; Pouta A; Zitting P; McArdle WL; Kroemer HK; Völker U; Völzke H; Glazer NL; Taylor KD; Harris TB; Alavere H; Haller T; Keis A; Tammesoo ML; Aulchenko Y; Barroso I; Khaw KT; Galan P; Hercberg S; Lathrop M; Eyheramendy S; Org E; Sõber S; Lu X; Nolte IM; Penninx BW; Corre T; Masciullo C; Sala C; Groop L; Voight BF; Melander O; O'Donnell CJ; Salomaa V; D'Adamo AP; Fabretto A; Faletra F; Ulivi S; Del Greco M F; Facheris M; Collins FS; Bergman RN; Beilby JP; Hung J; Musk AW; Mangino M; Shin SY; Soranzo N; Watkins H; Goel A; Hamsten A; Gider P; Loitfelder M; Zeginigg M; Hernandez D; Najjar SS; Navarro P; Wild SH; Corsi AM; Singleton A; de Geus EJ; Willemsen G; Parker AN; Rose LM; Buckley B; Stott D; Orru M; Uda M; LifeLines Cohort Study; van der Klauw MM; Zhang W; Li X; Scott J; Chen YD; Burke GL; Kähönen M; Viikari J; Döring A; Meitinger T; Davies G; Starr JM; Emilsson V; Plump A; Lindeman JH; Hoen PA; König IR; EchoGen consortium; Felix JF; Clarke R; Hopewell JC; Ongen H; Breteler M; Debette S; DeStefano AL; Fornage M; AortaGen Consortium; Mitchell GF; CHARGE Consortium Heart Failure Working Group; Smith NL; KidneyGen consortium; Holm H; Stefansson K; Thorleifsson G; Thorsteinsdottir U; CKDGen Consortium; Cardiogenics consortium; CARDIoGRAM Consortium; Samani NJ; Preuss M; Rudan I; Hayward C; Deary IJ; Wichmann HE; Raitakari OT; Palmas W; Kooner JS; Stolk RP; Jukema JW; Wright AF; Boomsma DI; Bandinelli S; Gyllensten UB; Wilson JF; Ferrucci L; Schmidt R; Farrall M; Spector TD; Palmer LJ; Tuomilehto J; Pfeufer A; Gasparini P; Siscovick D; Altshuler D; Loos RJ; Toniolo D; Snieder H; Gieger C; Meneton P; Wareham NJ; Oostra BA; Metspalu A; Launer L; Rettig R; Strachan DP; Beckmann JS; Witteman JC; Erdmann J; van Dijk KW; Boerwinkle E; Boehnke M; Ridker PM; Jarvelin MR; Chakravarti A; Abecasis GR; Gudnason V; Newton-Cheh C; Levy D; Munroe PB; Psaty BM; Caulfield MJ; Rao DC; Tobin MD; Elliott P; van Duijn CM (2011)
Numerous genetic loci have been associated with systolic blood pressure (SBP) and diastolic blood pressure (DBP) in Europeans. We now report genome-wide association studies of pulse pressure (PP) and mean arterial pressure ...

Search

Filters

Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

CUBN is a gene locus for albuminuria

Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels

Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk

Genome-wide association study identifies six new loci influencing pulse pressure and mean arterial pressure