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Hundreds of variants clustered in genomic loci and biological pathways affect human height
(2010)Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants ... -
Genome-wide association analysis identifies multiple loci related to resting heart rate
(2010)Higher resting heart rate is associated with increased cardiovascular disease and mortality risk. Though heritable factors play a substantial role in population variation, little is known about specific genetic determinants. ...