Now showing items 1-3 of 3

    • Co-occurrence of restless legs syndrome and Parkin mutations in two families 

      Adel S; Djarmati A; Kabakci K; Pichler I; Eskelson C; Lohnau T; Kock N; Hagenah J; Hedrich K; Schwinger E; Kramer PL; Pramstaller PP; Klein C (2006)
      Recent studies have suggested an association between restless legs syndrome (RLS) and Parkinson's disease (PD). We present a large multigenerational family and a smaller family with RLS. A Parkin mutation was found in 10 ...
    • Lewy body Parkinson's disease in a large pedigree with 77 Parkin mutation carriers 

      Pramstaller PP; Schlossmacher MG; Jacques TS; Scaravilli F; Eskelson C; Pepivani I; Hedrich K; Adel S; Gonzales-McNeal M; Hilker R; Kramer PL; Klein C (2005)
      We report the clinical, genetic, and neuropathological findings of a seven generation-spanning pedigree with 196 individuals, 25 of whom had levodopa-responsive parkinsonism. Genetic analyses indicated Parkin mutations in ...
    • Restless legs syndrome: epidemiological and clinicogenetic study in a South Tyrolean population isolate 

      Vogl FD; Pichler I; Adel S; Pinggera GK; Bracco S; De Grandi A; Volpato CB; Aridon P; Mayer T; Meitinger T; Klein C; Casari G; Pramstaller PP (2006)
      Genetic contributions to restless legs syndrome (RLS) have been consistently recognized from population and family studies. To determine the clinical and genetic features of RLS in a population isolate and explore linkage ...