Now showing items 1-1 of 1

    • SPOP mutation leads to genomic instability in prostate cancer 

      Boysen G; Barbieri C; Prandi D; Blattner M; Chae S; Dahija A; Nataraj S; Huang D; Marotz C; Xu L; Huang J; Lecca P; Chhangawala S; Liu D; Zhou P; Sboner A; Debono J; Demichelis F; Houvras Y; Rubin M (eLife Sciences Publications Ltd, 2015)
      Genomic instability is a fundamental feature of human cancer often resulting from impaired genome maintenance. In prostate cancer, structural genomic rearrangements are a common mechanism driving tumorigenesis. However, ...