Reversible Chirality Control in Peptide-Functionalized Gold Nanoparticles
MetadataShow full item record
SubjectSupramolecular chemistry; Peptide gold nanoparticle; Chiral gold nanoparticle; Circular dichroism; Helical peptides
We report the induction of chiroptical properties in 2 nm diameter gold nanoparticles passivated with short peptides characterized by the Aib-L-Ala repetition in their sequence. The nanoparticles present relevant ECD signals in the 300-650 nm wavelength region, corresponding to the gold nanoparticle's quantized electronic structure. Although the only chiral amino acid present in the peptide sequences is L-Ala, the particles show mirror image spectra like those of enantiomers according to the number of amino acids in the main chain (odd or even). Such a behavior appears to be strongly influenced by the secondary structure assumed by the peptides when passivating the nanoparticles and vanishes when the sequence is long enough to assume a 3(10)-helix conformation. Moreover, chirality control is a reversible process and can be deactivated or reactivated by increasing or decreasing the temperature.
Showing items related by title, author, creator and subject.
Peptide flatlandia: a new-concept peptide for positioning of electroactive probes in proximity to a metal surface Longo E; Wright K; Caruso M; Gatto E; Palleschi A; Scarselli M; De Crescenzi M; Crisma M; Formaggio F; Toniolo C; Venanzi M (ROYAL SOC CHEMISTRY, 2015)A helical hexapeptide was designed to link in a rigid parallel orientation to a gold surface. The peptide sequence of the newly synthesized compound is characterized by the presence of two 4-amino-1,2-dithiolane-4-carboxylic ...
Portioli C; Benati D; Pii Y; Bernardi P; Crucianelli M; Santucci S; Bentivoglio M; Passacantando M (2013)Cerium oxide nanoparticles, nanoceria, have been proposed as drug delivery devices and therapeutic tools also for neurological diseases due to their antioxidant properties and neuroprotective effects. However, very little ...
On the sintering of solution-based silver nanoparticle thin-films for sprayed and flexible antennas Bobinger M; Haider M; Goliya Y; Albrecht A; Becherer M; Lugli P; Rivadeneyra A; Russer J (IOP PUBLISHING LTD, 2018)In this work, we report on the fabrication and characterization of sub-300 nm electrode films based on solution-processed silver nanoparticles (AgNPs). Following the deposition of the electrode material using a scalable ...