Abstract
Unprecedented chiral oxacalixarenes were obtained from the reaction of (±)-1,1′-binaphthyl-2,2′-diol (BINOL) with 1,5-difluoro-2,4-dinitrobenzene. Structural elucidation of
C
2h-symmetric
meso (
R,
S)-oxacalix[4]arene and
D
2-symmetric racemic (as well as enantiopure) (
R,
R)- and (
S,
S)-oxacalix[4]arene was carried out by means of 1D and 2D NMR spectroscopy, ESI-MS, X-ray diffractometry, and circular dichroism spectroscopy.