Abstract
The paper presents the ICARUS Pedagogical Framework, or Reference model to address development of innovative pedagogical approaches to overcome the actual effectiveness problems in development, acquisition and application of the required knowledge and skills for the concepts related to Industry 4.0. The aim of the Pedagogical Framework is minimum twofold: 1) to define and guide and applications of innovative pedagogical methods to explore and address the needs of HEI educators and learners, and 2) to provide a model of the pedagogical methodology design space for future development and adaptations. In the send part of the paper a contribution to the formalization of the model using set theory approach is presented as well.