Computing organoids’ volume in medical images: the case study of cystic fibrosis

Paola Lecca; Michela Lecca; Paola Melotti; Virginia Lotti; Sara Preato; Karina Kleinfelder; Alessia Farinazzo; Claudio Sorio

doi:10.1109/CIBCB48159.2020.9277721

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Computing organoids’ volume in medical images: the case study of cystic fibrosis

Conference proceeding

Peer reviewed

Computing organoids’ volume in medical images: the case study of cystic fibrosis

Paola Lecca, Michela Lecca, Paola Melotti, Virginia Lotti, Sara Preato, Karina Kleinfelder, Alessia Farinazzo and Claudio Sorio

Proceedings of IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), Viña del Mar, 2020, pp.1-8

IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB) (Viña del Mar, 27/10/2020 - 29/11/2020)

2020

DOI: https://doi.org/10.1109/CIBCB48159.2020.9277721

Handle:

https://hdl.handle.net/10863/32602

Abstract

cystic fibrosis, cystic fibrosis transmembrane con-

ductance regulator, organoids, medical images, medical videos,

image processing, regression analysis

We present CORVO (Computing Organoids VOlume in medical images), a tool for calculating the volume of complex time-changing 3D structures from medical videos. In order to identify anisotropies in volume variation over time, CORVO is equipped with a module implementing an advanced regression-based statistical analysis. We tested CORVO for the analysis of the variation of rectal organoids volume, whose anisotropic or missing expansion indicates a pathological state and a non-response to a pharmacological treatment, respectively.

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https://ieeexplore.ieee.org/document/9277721/authors#authorsView

Details

Title: Computing organoids’ volume in medical images: the case study of cystic fibrosis
Creators: Paola Lecca - Free University of Bozen-Bolzano
Michela Lecca - Fondazione Bruno Kessler
Paola Melotti - Azienda Ospedaliera Universitaria Integrata Verona
Virginia Lotti - University of Verona
Sara Preato - University of Verona
Karina Kleinfelder - University of Verona
Alessia Farinazzo - University of Verona
Claudio Sorio - University of Verona
Publication Details: Proceedings of IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB), Viña del Mar, 2020, pp.1-8
ISBN: 9781728194691
EISBN: 9781728194684
Conference: IEEE Conference on Computational Intelligence in Bioinformatics and Computational Biology (CIBCB) (Viña del Mar, 27/10/2020 - 29/11/2020)
Publisher: IEEE
Format: Online
Identifiers: 978-1-7281-9469-1
(UNIBZ)38215055
991006490493601241
Scopus ID: 2-s2.0-85099063945
Academic Unit: Faculty of Computer Science
Language: English
Resource Type: Conference proceeding
Author Names String: Lecca P, Lecca M, Melotti P, Lotti V, Preato S, Kleinfelder K, Farinazzo A, Sorio C

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