Abstract
In this chapter, we explore after 10 years of Industry 4.0 the status of the application in manufacturing companies and especially in small- and medium-sized enterprises (SMEs). Based on literature and previously conducted research we present guidelines and a modular framework for implementing smart manufacturing in SMEs. In addition, a stage model is illustrated to support SMEs in breaking down the framework from a design level to an implementation and operational level. Finally, an outlook is given on the future challenges that SMEs will face in the coming years when they want to reach the next level of Industry 4.0 in their own company.