Abstract
A young athlete suddenly collapses in the middle of the sports field. The rescue team is unable to bring the young person back to life and can only determine cardiac arrest as cause of death. Cases like this are reported again and again and raise the question of how such a tragedy could happen so abruptly. One of the most common causes of sudden cardiac death in young people is hypertrophic cardiomyopathy, a congenital genetic disorder that affects one in 500. The underlying mechanisms are currently being investigated in the HYPER-FIBRO project.