Now showing items 1-2 of 2

    • Meta-analysis of genome-wide association studies in >80 000 subjects identifies multiple loci for C-reactive protein levels 

      Dehghan A; Dupuis J; Barbalic M; Bis JC; Eiriksdottir G; Lu C; Pellikka N; Wallaschofski H; Kettunen J; Henneman P; Baumert J; Strachan DP; Fuchsberger C; Vitart V; Wilson JF; Paré G; Naitza S; Rudock ME; Surakka I; de Geus EJ; Alizadeh BZ; Guralnik J; Shuldiner A; Tanaka T; Zee RY; Schnabel RB; Nambi V; Kavousi M; Ripatti S; Nauck M; Smith NL; Smith AV; Sundvall J; Scheet P; Liu Y; Ruokonen A; Rose LM; Larson MG; Hoogeveen RC; Freimer NB; Teumer A; Tracy RP; Launer LJ; Buring JE; Yamamoto JF; Folsom AR; Sijbrands EJ; Pankow J; Elliott P; Keaney JF; Sun W; Sarin AP; Fontes JD; Badola S; Astor BC; Hofman A; Pouta A; Werdan K; Greiser KH; Kuss O; Meyer Zu Schwabedissen H; Thiery J; Jamshidi Y; Nolte IM; Soranzo N; Spector TD; Völzke H; Parker AN; Aspelund T; Bates D; Young L; Tsui K; Siscovick DS; Guo X; Rotter JI; Uda M; Schlessinger D; Rudan I; Hicks AA; Penninx BW; Thorand B; Gieger C; Coresh J; Willemsen G; Harris TB; Uitterlinden AG; Järvelin MR; Rice K; Radke D; Salomaa V; Willems van Dijk K; Boerwinkle E; Vasan RS; Ferrucci L; Gibson QD; Bandinelli S; Snieder H; Boomsma DI; Xiao X; Campbell H; Hayward C; Pramstaller PP; van Duijn CM; Peltonen L; Psaty BM; Gudnason V; Ridker PM; Homuth G; Koenig W; Ballantyne CM; Witteman JC; Benjamin EJ; Perola M; Chasman DI (2011)
      BACKGROUND: C-reactive protein (CRP) is a heritable marker of chronic inflammation that is strongly associated with cardiovascular disease. We sought to identify genetic variants that are associated with CRP levels. METHODS ...
    • NFAT5 and SLC4A10 Loci Associate with Plasma Osmolality 

      Böger CA; Gorski M; McMahon GM; Xu H; Chang YC; van der Most PJ; Navis G; Nolte IM; de Borst MH; Zhang W; Lehne B; Loh M; Tan ST; Boerwinkle E; Grams ME; Sekula P; Li M; Wilmot B; Moon JG; Scheet P; Cucca F; Xiao X; Lyytikäinen LP; Delgado G; Grammer TB; Kleber ME; Sedaghat S; Rivadeneira F; Corre T; Kutalik Z; Bergmann S; Nielson CM; Srikanth P; Teumer A; Müller-Nurasyid M; Brockhaus AC; Pfeufer A; Rathmann W; Peters A; Matsumoto M; de Andrade M; Atkinson EJ; Robinson-Cohen C; de Boer IH; Hwang SJ; Heid IM; Gögele M; Concas MP; Tanaka T; Bandinelli S; Nalls MA; Singleton A; Tajuddin SM; Adeyemo A; Zhou J; Doumatey A; McWeeney S; Murabito J; Franceschini N; Flessner M; Shlipak M; Wilson JG; Chen G; Rotimi CN; Zonderman AB; Evans MK; Ferrucci L; Devuyst O; Pirastu M; Shuldiner A; Hicks AA; Pramstaller PP; Kestenbaum B; Kardia SL; Turner ST; Study LC; Briske TE; Gieger C; Strauch K; Meisinger C; Meitinger T; Völker U; Nauck M; Völzke H; Vollenweider P; Bochud M; Waeber G; Kähönen M; Lehtimäki T; März W; Dehghan A; Franco OH; Uitterlinden AG; Hofman A; Taylor HA; Chambers JC; Kooner JS; Fox CS; Hitzemann R; Orwoll ES; Pattaro C; Schlessinger D; Köttgen A; Snieder H; Parsa A; Cohen DM (2017)
      Disorders of water balance, an excess or deficit of total body water relative to body electrolyte content, are common and ascertained by plasma hypo- or hypernatremia, respectively. We performed a two-stage genome-wide ...