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  • Novel approach identifies SNPs in SLC2A10 and KCNK9 with evidence for parent-of-origin effect on body mass index 

    Hoggart CJ; Venturini G; Mangino M; Gomez F; Ascari G; Zhao JH; Teumer A; Winkler TW; Tšernikova N; Luan J; Mihailov E; Ehret GB; Zhang W; Lamparter D; Esko T; Macé A; Rüeger S; Bochud PY; Barcella M; Dauvilliers Y; Benyamin B; Evans DM; Hayward C; Lopez MF; Franke L; Russo A; Heid IM; Salvi E; Vendantam S; Arking DE; Boerwinkle E; Chambers JC; Fiorito G; Grallert H; Guarrera S; Homuth G; Huffman JE; Porteous D; Generation Scotland Consortium; LifeLines Cohort study; GIANT Consortium; Moradpour D; Iranzo A; Hebebrand J; Kemp JP; Lammers GJ; Aubert V; Heim MH; Martin NG; Montgomery GW; Peraita-Adrados R; Santamaria J; Negro F; Schmidt CO; Scott RA; Spector TD; Strauch K; Völzke H; Wareham NJ; Yuan W; Bell JT; Chakravarti A; Kooner JS; Peters A; Matullo G; Wallaschofski H; Whitfield JB; Paccaud F; Vollenweider P; Bergmann S; Beckmann JS; Tafti M; Hastie ND; Cusi D; Bochud M; Frayling TM; Metspalu A; Jarvelin MR; Scherag A; Smith GD; Borecki IB; Rousson V; Hirschhorn JN; Rivolta C; Loos RJ; Kutalik Z (2014)
    The phenotypic effect of some single nucleotide polymorphisms (SNPs) depends on their parental origin. We present a novel approach to detect parent-of-origin effects (POEs) in genome-wide genotype data of unrelated ...