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    • Target genes, variants, tissues and transcriptional pathways influencing human serum urate levels 

      Tin A; Marten J; Halperin Kuhns VL; Li Y; Wuttke M; Kirsten H; Sieber KB; Qiu C; Gorski M; Yu Z; Giri A; Sveinbjornsson G; Li M; Chu AY; Hoppmann A; O'Connor LJ; Prins B; Nutile T; Noce D; Akiyama M; Cocca M; Ghasemi S; van der Most PJ; Horn K; Xu Y; Fuchsberger C; Sedaghat S; Afaq S; Amin N; Ärnlöv J; Bakker SJL; Bansal N; Baptista D; Bergmann S; Biggs ML; Biino G; Boerwinkle E; Bottinger EP; Boutin TS; Brumat M; Burkhardt R; Campana E; Campbell A; Campbell H; Carroll RJ; Catamo E; Chambers JC; Ciullo M; Concas MP; Coresh J; Corre T; Cusi D; Felicita SC; de Borst MH; De Grandi A; de Mutsert R; de Vries APJ; Delgado G; Demirkan A; Devuyst O; Dittrich K; Eckardt KU; Ehret G; Endlich K; Evans MK; Gansevoort RT; Gasparini P; Giedraitis V; Gieger C; Girotto G; Gögele M; Gordon SD; Gudbjartsson DF; Gudnason V; Haller T; Hamet P; Harris TB; Hayward C; Hicks AA; Hofer E; Holm H; Huang W; Hutri-Kähönen N; Hwang SJ; Ikram MA; Lewis RM; Ingelsson E; Jakobsdottir J; Jonsdottir I; Jonsson H; Joshi PK; Josyula NS; Jung B; Kähönen M; Kamatani Y; Kanai M; Kerr SM; Kiess W; Kleber ME; Koenig W; Kooner JS; Körner A; Kovacs P; Krämer BK; Kronenberg F; Kubo M; Kühnel B; La Bianca M; Lange LA; Lehne B; Lehtimäki T; Liu J; Loeffler M; Loos RJF; Lyytikäinen LP; Magi R; Mahajan A; Martin NG; März W; Mascalzoni D; Matsuda K; Meisinger C; Meitinger T; Metspalu A; Milaneschi Y; O'Donnell CJ; Wilson OD; Gaziano JM; Mishra PP; Mohlke KL; Mononen N; Montgomery GW; Mook-Kanamori DO; Müller-Nurasyid M; Nadkarni GN; Nalls MA; Nauck M; Nikus K; Ning B; Nolte IM; Noordam R; O'Connell JR; Olafsson I; Padmanabhan S; Penninx BWJH; Perls T; Peters A; Pirastu M; Pirastu N; Pistis G; Polasek O; Ponte B; Porteous DJ; Poulain T; Preuss MH; Rabelink TJ; Raffield LM; Raitakari OT; Rettig R; Rheinberger M; Rice KM; Rizzi F; Robino A; Rudan I; Krajcoviechova A; Cifkova R; Rueedi R; Ruggiero D; Ryan KA; Saba Y; Salvi E; Schmidt H; Schmidt R; Shaffer CM; Smith AV; Smith BH; Spracklen CN; Strauch K; Stumvoll M; Sulem P; Tajuddin SM; Teren A; Thiery J; Thio CHL; Thorsteinsdottir U; Toniolo D; Tönjes A; Tremblay J; Uitterlinden AG; Vaccargiu S; van der Harst P; van Duijn CM; Verweij N; Völker U; Vollenweider P; Waeber G; Waldenberger M; Whitfield JB; Wild SH; Wilson JF; Yang Q; Zhang W; Zonderman AB; Bochud M; Wilson JG; Pendergrass SA; Ho K; Parsa A; Pramstaller PP; Psaty BM; Böger CA; Snieder H; Butterworth AS; Okada Y; Edwards TL; Stefansson K; Susztak K; Scholz M; Heid IM; Hung AM; Teumer A; Pattaro C; Woodward OM; Vitart V; Köttgen A (2019)
      Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via poorly understood mechanisms. We performed a trans-ancestry genome-wide association study of serum urate in 457,690 individuals, ...