Now showing items 1-4 of 4

    • Genome-wide association study identifies a novel locus contributing to type 2 diabetes susceptibility in Sikhs of Punjabi origin from India 

      Saxena R; Saleheen D; Been LF; Garavito ML; Braun T; Bjonnes A; Young R; Ho WK; Rasheed A; Frossard P; Sim X; Hassanali N; Radha V; Chidambaram M; Liju S; Rees SD; Ng DP; Wong TY; Yamauchi T; Hara K; Tanaka Y; Hirose H; McCarthy MI; Morris AP; DIAGRAM Consortium; MuTHER Consortium; AGEN; Basit A; Barnett AH; Katulanda P; Matthews D; Mohan V; Wander GS; Singh JR; Mehra NK; Ralhan S; Kamboh MI; Mulvihill JJ; Maegawa H; Tobe K; Maeda S; Cho YS; Tai ES; Kelly MA; Chambers JC; Kooner JS; Kadowaki T; Deloukas P; Rader DJ; Danesh J; Sanghera DK (2013)
      We performed a genome-wide association study (GWAS) and a multistage meta-analysis of type 2 diabetes (T2D) in Punjabi Sikhs from India. Our discovery GWAS in 1,616 individuals (842 case subjects) was followed by in silico ...
    • Genome-wide association study identifies three novel loci for type 2 diabetes 

      Hara K; Fujita H; Johnson TA; Yamauchi T; Yasuda K; Horikoshi M; Peng C; Hu C; Ma RC; Imamura M; Iwata M; Tsunoda T; Morizono T; Shojima N; So WY; Leung TF; Kwan P; Zhang R; Wang J; Yu W; Maegawa H; Hirose H; DIAGRAM Consortium; Kaku K; Ito C; Watada H; Tanaka Y; Tobe K; Kashiwagi A; Kawamori R; Jia W; Chan JC; Teo YY; Shyong TE; Kamatani N; Kubo M; Maeda S; Kadowaki T (2014)
      Although over 60 loci for type 2 diabetes (T2D) have been identified, there still remains a large genetic component to be clarified. To explore unidentified loci for T2D, we performed a genome-wide association study (GWAS) ...
    • Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians 

      Cho YS; Chen CH; Hu C; Long J; Ong RT; Sim X; Takeuchi F; Wu Y; Go MJ; Yamauchi T; Chang YC; Kwak SH; Ma RC; Yamamoto K; Adair LS; Aung T; Cai Q; Chang LC; Chen YT; Gao Y; Hu FB; Kim HL; Kim S; Kim YJ; Lee JJ; Lee NR; Li Y; Liu JJ; Lu W; Nakamura J; Nakashima E; Ng DP; Tay WT; Tsai FJ; Wong TY; Yokota M; Zheng W; Zhang R; Wang C; So WY; Ohnaka K; Ikegami H; Hara K; Cho YM; Cho NH; Chang TJ; Bao Y; Hedman ÅK; Morris AP; McCarthy MI; DIAGRAM Consortium; MuTHER Consortium; Takayanagi R; Park KS; Jia W; Chuang LM; Chan JC; Maeda S; Kadowaki T; Lee JY; Wu JY; Teo YY; Tai ES; Shu XO; Mohlke KL; Kato N; Han BG; Seielstad M (2011)
      We conducted a three-stage genetic study to identify susceptibility loci for type 2 diabetes (T2D) in east Asian populations. We followed our stage 1 meta-analysis of eight T2D genome-wide association studies (6,952 cases ...
    • A single-nucleotide polymorphism in ANK1 is associated with susceptibility to type 2 diabetes in Japanese populations 

      Imamura M; Maeda S; Yamauchi T; Hara K; Yasuda K; Morizono T; Takahashi A; Horikoshi M; Nakamura M; Fujita H; Tsunoda T; Kubo M; Watada H; Maegawa H; Okada-Iwabu M; Iwabu M; Shojima N; Ohshige T; Omori S; Iwata M; Hirose H; Kaku K; Ito C; Tanaka Y; Tobe K; Kashiwagi A; Kawamori R; Kasuga M; Kamatani N; DIAGRAM Consortium; Nakamura Y; Kadowaki T (2012)
      To identify a novel susceptibility locus for type 2 diabetes, we performed an imputation-based, genome-wide association study (GWAS) in a Japanese population using newly obtained imputed-genotype data for 2 229 890 ...