Now showing items 1-3 of 3

    • Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization 

      Arking DE; Pulit SL; Crotti L; van der Harst P; Munroe PB; Koopmann TT; Sotoodehnia N; Rossin EJ; Morley M; Wang X; Johnson AD; Lundby A; Gudbjartsson DF; Noseworthy PA; Eijgelsheim M; Bradford Y; Tarasov KV; Dörr M; Müller-Nurasyid M; Lahtinen AM; Nolte IM; Smith AV; Bis JC; Isaacs A; Newhouse SJ; Evans DS; Post WS; Waggott D; Lyytikäinen LP; Hicks AA; Eisele L; Ellinghaus D; Hayward C; Navarro P; Ulivi S; Tanaka T; Tester DJ; Chatel S; Gustafsson S; Kumari M; Morris RW; Naluai ÅT; Padmanabhan S; Kluttig A; Strohmer B; Panayiotou AG; Torres M; Knoflach M; Hubacek JA; Slowikowski K; Raychaudhuri S; Kumar RD; Harris TB; Launer LJ; Shuldiner AR; Alonso A; Bader JS; Ehret G; Huang H; Kao WH; Strait JB; Macfarlane PW; Brown M; Caulfield MJ; Samani NJ; Kronenberg F; Willeit J; CARe Consortium; COGENT Consortium; Smith JG; Greiser KH; Meyer Zu Schwabedissen H; Werdan K; Carella M; Zelante L; Heckbert SR; Psaty BM; Rotter JI; Kolcic I; Polašek O; Wright AF; Griffin M; Daly MJ; DCCT/EDIC; Arnar DO; Hólm H; Thorsteinsdottir U; eMERGE Consortium; Denny JC; Roden DM; Zuvich RL; Emilsson V; Plump AS; Larson MG; O'Donnell CJ; Yin X; Bobbo M; D'Adamo AP; Iorio A; Sinagra G; Carracedo A; Cummings SR; Nalls MA; Jula A; Kontula KK; Marjamaa A; Oikarinen L; Perola M; Porthan K; Erbel R; Hoffmann P; Jöckel KH; Kälsch H; Nöthen MM; HRGEN Consortium; den Hoed M; Loos RJ; Thelle DS; Gieger C; Meitinger T; Perz S; Peters A; Prucha H; Sinner MF; Waldenberger M; de Boer RA; Franke L; van der Vleuten PA; Beckmann BM; Martens E; Bardai A; Hofman N; Wilde AA; Behr ER; Dalageorgou C; Giudicessi JR; Medeiros-Domingo A; Barc J; Kyndt F; Probst V; Ghidoni A; Insolia R; Hamilton RM; Scherer SW; Brandimarto J; Margulies K; Moravec CE; Del Greco M F; Fuchsberger C; O'Connell JR; Lee WK; Watt GC; Campbell H; Wild SH; El Mokhtari NE; Frey N; Asselbergs FW; Mateo Leach I; Navis G; van den Berg MP; van Veldhuisen DJ; Kellis M; Krijthe BP; Franco OH; Hofman A; Kors JA; Uitterlinden AG; Witteman JC; Kedenko L; Lamina C; Oostra BA; Abecasis GR; Lakatta EG; Mulas A; Orrú M; Schlessinger D; Uda M; Markus MR; Völker U; Snieder H; Spector TD; Ärnlöv J; Lind L; Sundström J; Syvänen AC; Kivimaki M; Kähönen M; Mononen N; Raitakari OT; Viikari JS; Adamkova V; Kiechl S; Brion M; Nicolaides AN; Paulweber B; Haerting J; Dominiczak AF; Nyberg F; Whincup PH; Hingorani AD; Schott JJ; Bezzina CR; Ingelsson E; Ferrucci L; Gasparini P; Wilson JF; Rudan I; Franke A; Mühleisen TW; Pramstaller PP; Lehtimäki TJ; Paterson AD; Parsa A; Liu Y; van Duijn CM; Siscovick DS; Gudnason V; Jamshidi Y; Salomaa V; Felix SB; Sanna S; Ritchie MD; Stricker BH; Stefansson K; Boyer LA; Cappola TP; Olsen JV; Lage K; Schwartz PJ; Kääb S; Chakravarti A; Ackerman MJ; Pfeufer A; de Bakker PI; Newton-Cheh C (2014)
      The QT interval, an electrocardiographic measure reflecting myocardial repolarization, is a heritable trait. QT prolongation is a risk factor for ventricular arrhythmias and sudden cardiac death (SCD) and could indicate ...
    • Genome-wide association meta-analysis of PR interval identifies 50 novel loci associated with atrial and atrioventricular electrical activity 

      van Setten J; Brody JA; Jamshidi Y; Swenson BR; Butler AM; Campbell H; Del Greco M F; Evans DS; Gibson Q; Gudbjartsson DF; Kerr KF; Krijthe BP; Lyytikäinen LP; Müller C; Müller-Nurasyid M; Nolte IM; Padmanabhan S; Ritchie MD; Robino A; Smith AV; Steri M; Tanaka T; Teumer A; Trompet S; Ulivi S; Verweij N; Yin X; Arnar DO; Asselbergs FW; Bader JS; Barnard J; Bis S; Blankenberg S; Boerwinkle E; Bradford Y; Buckley BM; Chung MK; Crawford D; den Hoed M; Denny JC; Dominiczak AF; Ehret GB; Eijgelsheim M; Ellinor PT; Felix SB; Franco OH; Franke L; Harris TB; Holm H; Gandin I; Iorio A; Kähönen M; Kolcic I; Kors JA; Lakatta EG; Launer LJ; Lin H; Lin HJ; Loos RJF; Lubitz SA; Macfarlane PW; Magnani JW; Mateo Leach I; Meitinger T; Mitchell BD; Munzel T; Papanicolaou GJ; Peters A; Pfeufer A; Pramstaller PP; Raitakari OT; Rotter JI; Rudan I; Samani NJ; Schlessinger D; Silva Aldana CT; Sinner MF; Smith JD; Snieder H; Soliman EZ; Spector TD; Stott DJ; Strauch K; Tarasov KV; Thorsteinsdottir U; Uitterlinden AG; Van Wagoner DR; Völker U; Völzke H; Waldenberger M; Jan Westra H; Wild PS; Zeller T; Alonso A; Avery CL; Bandinelli S; Benjamin EJ; Cucca F; Dörr M; Ferrucci L; Gasparini P; Gudnason V; Hayward C; Heckbert SR; Hicks AA; Wouter Jukema J; Kääb S; Lehtimäki T; Liu Y; Munroe PB; Parsa A; Polasek O; Psaty BM; Roden DM; Schnabel RB; Sinagra G; Stefansson K; Stricker BH; van der Harst P; van Duijn CM; Wilson JF; Gharib SA; de Bakker PIW; Isaacs A; Arking DE; Sotoodehnia N (2018)
      Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome-wide association study of over 92,000 ...
    • PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity 

      vvan Setten J; Brody JA; Jamshidi Y; Swenson BR; Butler AM; Campbell H; Del Greco M F; Evans DS; Gibson Q; Gudbjartsson DF; Kerr KF; Krijthe BP; Lyytikäinen LP; Müller C; Müller-Nurasyid M; Nolte IM; Padmanabhan S; Ritchie MD; Robino A; Smith AV; Steri M; Tanaka T; Teumer A; Trompet S; Ulivi S; Verweij N; Yin X; Arnar DO; Asselbergs FW; Bader JS; Barnard J; Bis J; Blankenberg S; Boerwinkle E; Bradford Y; Buckley BM; Chung MK; Crawford D; den Hoed M; Denny JC; Dominiczak AF; Ehret GB; Eijgelsheim M; Ellinor PT; Felix SB; Franco OH; Franke L; Harris TB; Holm H; Ilaria G; Iorio A; Kähönen M; Kolcic I; Kors JA; Lakatta EG; Launer LJ; Lin H; Lin HJ; Loos RJF; Lubitz SA; Macfarlane PW; Magnani JW; Leach IM; Meitinger T; Mitchell BD; Munzel T; Papanicolaou GJ; Peters A; Pfeufer A; Pramstaller PP; Raitakari OT; Rotter JI; Rudan I; Samani NJ; Schlessinger D; Silva Aldana CT; Sinner MF; Smith JD; Snieder H; Soliman EZ; Spector TD; Stott DJ; Strauch K; Tarasov KV; Thorsteinsdottir U; Uitterlinden AG; Van Wagoner DR; Völker U; Völzke H; Waldenberger M; Jan Westra H; Wild PS; Zeller T; Alonso A; Avery CL; Bandinelli S; Benjamin EJ; Cucca F; Dörr M; Ferrucci L; Gasparini P; Gudnason V; Hayward C; Heckbert SR; Hicks AA; Jukema JW; Kääb S; Lehtimäki T; Liu Y; Munroe PB; Parsa A; Polasek O; Psaty BM; Roden DM; Schnabel RB; Sinagra G; Stefansson K; Stricker BH; van der Harst P; van Duijn CM; Wilson JF; Gharib SA; de Bakker PIW; Isaacs A; Arking DE; Sotoodehnia N (2018)
      Electrocardiographic PR interval measures atrio-ventricular depolarization and conduction, and abnormal PR interval is a risk factor for atrial fibrillation and heart block. Our genome-wide association study of over 92,000 ...